Davies J, Rosenthal M, Bush A
Department of Paediatric Respiratory Medicine, Royal Bromptom Hospital, London, England.
J R Soc Med. 1996 Mar;89(3):172P-3P.
At the age of 12, a child with cystic fibrosis developed severe small airways obstruction of unknown aetiology, in the absence of significant bronchiectasis. He remained resistant to medical treatment until, following an exacerbation of allergic bronchopulmonary aspergillosis 18 months later, he responded to high dose oral steroids. He now remains steroid-dependent, and suffering from multiple side-effects. Possible aetiology and further therapeutic strategies are discussed.
一名12岁的囊性纤维化患儿出现了病因不明的严重小气道阻塞，且无明显支气管扩张。在18个月后过敏性支气管肺曲霉菌病加重之前，他对药物治疗一直没有反应，之后对高剂量口服类固醇产生了反应。他现在仍然依赖类固醇，并遭受多种副作用。本文讨论了可能的病因及进一步的治疗策略。
