Beglinger C
Abteilung für Gastroenterologie, Kantonsspital, Basel.
Ther Umsch. 1996 May;53(5):354-8.
Chronic pancreatitis is a chronic, inflammatory process leading to destruction of the exocrine tissue, filorosis, and in some patients a loss of endocrine function. Because chronic pancreatitis results in a permanent destruction of pancreatic tissue, exocrine and/or endocrine pancreatic insufficiency may follow. However, owing to the tremendous reserve of pancreatic function, insufficiency may be subclinical at least in the beginning of the disease. The diagnosis of chronic pancreatitis is not difficult; it is based on a typical medical history, specific imaging procedures, and pancreatic function testing. The main differential diagnosis is to separate chronic pancreatitis form pancreatic carcinoma. In the present summary, the different imaging procedures and pancreatic function tests are discussed.
慢性胰腺炎是一种慢性炎症过程,可导致外分泌组织破坏、纤维化,部分患者还会出现内分泌功能丧失。由于慢性胰腺炎会导致胰腺组织永久性破坏,随后可能出现胰腺外分泌和/或内分泌功能不全。然而,由于胰腺功能储备巨大,至少在疾病初期,功能不全可能处于亚临床状态。慢性胰腺炎的诊断并不困难;它基于典型的病史、特定的影像学检查和胰腺功能测试。主要的鉴别诊断是将慢性胰腺炎与胰腺癌区分开来。在本综述中,将讨论不同的影像学检查和胰腺功能测试。