Kannan K, Corsolini S, Focardi S, Tanabe S, Tatsukawa R
Department of Environment Conservation, Ehime University, Tarumi 3-5-7, Matsuyama 790, Japan.
Arch Environ Contam Toxicol. 1996 Jul;31(1):19-23. doi: 10.1007/BF00203903.
Tributyltin (TBT) and its breakdown products, mono-(MBT) and dibutyltin (DBT) were determined in bottlenose dolphin (Tursiops truncatus), bluefin tuna (Thunnus thynnus thynnus) and blue shark (Prionace glauca) collected from the Italian coast of the Mediterranean Sea in 1992-1993. Concentrations of total butyltin (BTs) in the liver of dolphin (1,200-2,200 ng/g wet wt) were an order of magnitude higher than in the blubber (48-320 ng/g wet wt). TBT was the predominant butyltin species in the blubber while DBT accounted for an higher proportion in the liver of dolphins. Butyltin concentrations in bluefin tuna were lower than those in dolphins, with TBT highest in the muscle and DBT in the liver. Concentrations of BTs in blue sharks were lower than those in dolphin and tuna, with kidney having the highest concentrations. TBT was the predominant form of butyltin derivatives in all the tissues of shark. Accumulation of butyltin compounds in liver/kidney seems to be associated with the presence of proteins such as glutathione.
1992年至1993年期间，对从地中海意大利海岸捕获的宽吻海豚（瓶鼻海豚）、蓝鳍金枪鱼和大青鲨体内的三丁基锡（TBT）及其分解产物单丁基锡（MBT）和二丁基锡（DBT）进行了测定。海豚肝脏中总丁基锡（BTs）的浓度（1200 - 2200纳克/克湿重）比其鲸脂中的浓度（48 - 320纳克/克湿重）高一个数量级。在鲸脂中，TBT是主要的丁基锡种类，而在海豚肝脏中，DBT所占比例更高。蓝鳍金枪鱼体内的丁基锡浓度低于海豚，肌肉中TBT含量最高，肝脏中DBT含量最高。大青鲨体内的BTs浓度低于海豚和金枪鱼，肾脏中的浓度最高。TBT是鲨鱼所有组织中丁基锡衍生物的主要形式。肝脏/肾脏中丁基锡化合物的积累似乎与谷胱甘肽等蛋白质的存在有关。
