Lebowitz M D, Burrows B
Am J Epidemiol. 1977 Jun;105(6):544-54. doi: 10.1093/oxfordjournals.aje.a112418.
Several studies have suggested that acute respiratory illnesses (ARI) may be precursors to chronic obstructive lung diseases, as well as being exacerbations of such diseases. The relationship of retrospective and prospective data on ARI to the prevalence and incidence of obstructive lung disorders has been examined in the community epidemiologic study of obstructive diseases a longitudinal study in Tucson. It has been determined that both the previous and subsequent history of ARI are significantly associated with the prevalence and incidence of airways obstructive diseases, those diagnosed by physicians and those inferred by symptoms. Lung function impairment also appears to be associated with such illnesses. This study implicates ARI as one of the major factors associated with the etiology as well as the natural history of chronic obstructive lung disease.
多项研究表明，急性呼吸道疾病（ARI）可能是慢性阻塞性肺疾病的先兆，也是此类疾病的加重因素。在图森进行的一项关于阻塞性疾病的纵向社区流行病学研究中，对ARI的回顾性和前瞻性数据与阻塞性肺疾病的患病率和发病率之间的关系进行了研究。已确定，ARI的既往史和后续病史均与气道阻塞性疾病的患病率和发病率显著相关，这些疾病由医生诊断以及根据症状推断得出。肺功能损害似乎也与此类疾病有关。这项研究表明，ARI是与慢性阻塞性肺疾病的病因以及自然史相关的主要因素之一。
