The use of testicular sperm for intracytoplasmic sperm injection in patients with necrozoospermia.
作者信息
Tournaye H, Liu J, Nagy Z, Verheyen G, Van Steirteghem A, Devroey P
机构信息
Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University, Brussels, Belgium.
出版信息
Fertil Steril. 1996 Aug;66(2):331-4. doi: 10.1016/s0015-0282(16)58462-3.
OBJECTIVE
To investigate whether intracytoplasmic sperm injection (ICSI) using testicular spermatozoa from necrozoospermic patients results in acceptable fertilization and transfer rates.
DESIGN
Retrospective clinical study.
SETTING
Tertiary referral center.
PATIENTS
Five patients presenting consistently with 100% dead spermatozoa in their ejaculates.
INTERVENTIONS
In seven treatment cycles, an open testicular biopsy was performed to increase the chances for retrieving viable spermatozoa which were used for ICSI.
MAIN OUTCOME MEASURES
Sperm recovery, fertilization, and transfer rates.
RESULTS
Testicular sperm were recovered in all treatment cycles and fertilization occurred in six of seven cycles. Overall normal fertilization and transfer rates were 67% and 71%, respectively. One live birth was obtained after five ETs.
CONCLUSION
We recommend testicular sperm recovery for ICSI in patients who invariably or occasionally present with absolute necrozoospermia.
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