Tournaye H, Liu J, Nagy Z, Verheyen G, Van Steirteghem A, Devroey P
Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University, Brussels, Belgium.
Fertil Steril. 1996 Aug;66(2):331-4. doi: 10.1016/s0015-0282(16)58462-3.
To investigate whether intracytoplasmic sperm injection (ICSI) using testicular spermatozoa from necrozoospermic patients results in acceptable fertilization and transfer rates.
Retrospective clinical study.
Tertiary referral center.
Five patients presenting consistently with 100% dead spermatozoa in their ejaculates.
In seven treatment cycles, an open testicular biopsy was performed to increase the chances for retrieving viable spermatozoa which were used for ICSI.
Sperm recovery, fertilization, and transfer rates.
Testicular sperm were recovered in all treatment cycles and fertilization occurred in six of seven cycles. Overall normal fertilization and transfer rates were 67% and 71%, respectively. One live birth was obtained after five ETs.
We recommend testicular sperm recovery for ICSI in patients who invariably or occasionally present with absolute necrozoospermia.
