Models of T cell anergy: is there a common molecular mechanism?
作者信息
Schwartz R H
机构信息
Laboratory of Cellular and Molecular Immunology, National Institutes of Health, Bethesda, Maryland 20892-0420, USA.
出版信息
J Exp Med. 1996 Jul 1;184(1):1-8. doi: 10.1084/jem.184.1.1.
Abstract
摘要
相似文献
1
Models of T cell anergy: is there a common molecular mechanism?T细胞无能模型：是否存在共同的分子机制？
J Exp Med. 1996 Jul 1;184(1):1-8. doi: 10.1084/jem.184.1.1.
2
Induction of T-cell anergy by OKT3 requires cyclosporine-insensitive activation signals.
Transplant Proc. 1995 Feb;27(1):1425-7.
3
T cell anergy: where it's LAT.T细胞无能：LAT的作用所在。
Immunity. 2006 May;24(5):501-3. doi: 10.1016/j.immuni.2006.05.002.
4
A logical analysis of T cell activation and anergy.T细胞活化与无反应性的逻辑分析。
Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3894-9. doi: 10.1073/pnas.96.7.3894.
5
Induction of T cell anergy by low numbers of agonist ligands.低数量激动剂配体诱导T细胞无能
J Immunol. 1999 Jun 1;162(11):6401-9.
6
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy.二酰甘油代谢的破坏会损害T细胞无反应性的诱导。
Nat Immunol. 2006 Nov;7(11):1174-81. doi: 10.1038/ni1400. Epub 2006 Oct 8.
7
T-cell anergy.T细胞失能
Curr Opin Immunol. 2004 Apr;16(2):209-16. doi: 10.1016/j.coi.2004.01.013.
8
Interleukin-2, but not interleukin-15, is required to terminate experimentally induced clonal T-cell anergy.终止实验诱导的克隆性T细胞无反应性需要白细胞介素-2，但不需要白细胞介素-15。
Scand J Immunol. 2004 Jul-Aug;60(1-2):64-73. doi: 10.1111/j.0300-9475.2004.01446.x.
9
The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells.诱导共刺激分子（ICOS）在指导T细胞应答中的作用：耐受性树突状细胞对T细胞无能的ICOS依赖性诱导。
J Immunol. 2009 Mar 15;182(6):3349-56. doi: 10.4049/jimmunol.0802733.
10
Dissecting the mechanism of T-cell anergy with immunophilin ligands.用亲免素配体剖析T细胞无能的机制。
Curr Opin Investig Drugs. 2006 Nov;7(11):1002-7.
引用本文的文献
1
Cellular Components of the Tumor Environment in Gliomas-What Do We Know Today?神经胶质瘤肿瘤微环境的细胞组成——我们如今了解多少？
Biomedicines. 2023 Dec 20;12(1):14. doi: 10.3390/biomedicines12010014.
2
The interplay of inflammation, exosomes and Ca dynamics in diabetic cardiomyopathy.糖尿病心肌病中炎症、外泌体和钙动态的相互作用。
Cardiovasc Diabetol. 2023 Feb 20;22(1):37. doi: 10.1186/s12933-023-01755-1.
3
Mapping CAR T-Cell Design Space Using Agent-Based Models.使用基于智能体的模型绘制嵌合抗原受体T细胞设计空间
Front Mol Biosci. 2022 Jul 12;9:849363. doi: 10.3389/fmolb.2022.849363. eCollection 2022.
4
The optimized core peptide derived from CABIN1 efficiently inhibits calcineurin-mediated T-cell activation.优化的核心肽源自 CABIN1，能有效抑制钙调神经磷酸酶介导的 T 细胞活化。
Exp Mol Med. 2022 May;54(5):613-625. doi: 10.1038/s12276-022-00772-6. Epub 2022 May 12.
5
Effect of Cellular-Based Artificial Antigen Presenting Cells Expressing ICOSL, in T-cell Subtypes Differentiation and Activation.表达ICOSL的细胞型人工抗原呈递细胞在T细胞亚群分化和激活中的作用
Adv Pharm Bull. 2021 May;11(3):537-542. doi: 10.34172/apb.2021.062. Epub 2020 Aug 5.
6
Optimization of T-cell Receptor-Modified T Cells for Cancer Therapy.优化 TCR 修饰 T 细胞用于癌症治疗。
Cancer Immunol Res. 2020 Jun;8(6):743-755. doi: 10.1158/2326-6066.CIR-19-0910. Epub 2020 Mar 24.
7
CaMKII Activity in the Inflammatory Response of Cardiac Diseases.钙调蛋白依赖性蛋白激酶 II 在心脏疾病炎症反应中的活性。
Int J Mol Sci. 2019 Sep 6;20(18):4374. doi: 10.3390/ijms20184374.
8
Immunoregulatory pathways following strong inflammatory processes markedly impair CD4+ T cell responses.强烈炎症过程后的免疫调节途径会显著损害CD4+ T细胞反应。
Hum Vaccin Immunother. 2016 Sep;12(9):2249-52. doi: 10.1080/21645515.2016.1174357. Epub 2016 Jul 13.
9
Engagement of distinct epitopes on CD43 induces different co-stimulatory pathways in human T cells.CD43上不同表位的结合在人T细胞中诱导不同的共刺激途径。
Immunology. 2016 Nov;149(3):280-296. doi: 10.1111/imm.12642. Epub 2016 Aug 16.
10
Induction of tolerance against the arthritogenic antigen with type-II collagen peptide-linked soluble MHC class II molecules.利用II型胶原肽连接的可溶性MHC II类分子诱导对致关节炎抗原的耐受性。
BMB Rep. 2016 Jun;49(6):331-6. doi: 10.5483/bmbrep.2016.49.6.207.
本文引用的文献
1
Inactivation of human immunodeficiency virus (HIV)-1 envelope-specific CD8+ cytotoxic T lymphocytes by free antigenic peptide: a self-veto mechanism?游离抗原肽对人免疫缺陷病毒（HIV）-1包膜特异性CD8 + 细胞毒性T淋巴细胞的失活作用：一种自我否决机制？
J Exp Med. 1996 Mar 1;183(3):879-89. doi: 10.1084/jem.183.3.879.
2
Blocked Ras activation in anergic CD4+ T cells.无反应性CD4 + T细胞中Ras激活受阻。
Science. 1996 Mar 1;271(5253):1276-8. doi: 10.1126/science.271.5253.1276.
3
Blocked signal transduction to the ERK and JNK protein kinases in anergic CD4+ T cells.无反应性CD4+ T细胞中ERK和JNK蛋白激酶的信号转导受阻。
Science. 1996 Mar 1;271(5253):1272-6. doi: 10.1126/science.271.5253.1272.
4
In vivo anergized CD4+ T cells express perturbed AP-1 and NF-kappa B transcription factors.体内失能的CD4⁺ T细胞表达异常的AP-1和NF-κB转录因子。
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):979-84. doi: 10.1073/pnas.93.3.979.
5
CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation.在缺乏磷脂酰肌醇3-激酶结合与激活的情况下，CD28介导的共刺激作用
Mol Cell Biol. 1995 Dec;15(12):6820-8. doi: 10.1128/MCB.15.12.6820.
6
Human interleukin-10 can directly inhibit T-cell growth.人白细胞介素-10可直接抑制T细胞生长。
Blood. 1993 Jun 1;81(11):2964-71.
7
Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells.活抗原呈递细胞上改变的T细胞受体配体诱导T细胞无能
Nature. 1993 May 13;363(6425):156-9. doi: 10.1038/363156a0.
8
Multiple levels of peripheral tolerance.外周耐受的多个层面。
Immunol Today. 1993 Jan;14(1):12-4. doi: 10.1016/0167-5699(93)90317-E.
9
CD28 mRNA rapidly decays when activated T cells are functionally anergized with specific peptide.当活化的T细胞被特定肽功能性失能时，CD28信使核糖核酸迅速降解。
Int Immunol. 1993 May;5(5):461-6. doi: 10.1093/intimm/5.5.461.
10
Protease inhibitors selectively block T cell receptor-triggered programmed cell death in a murine T cell hybridoma and activated peripheral T cells.蛋白酶抑制剂可选择性地阻断小鼠T细胞杂交瘤和活化的外周T细胞中T细胞受体触发的程序性细胞死亡。
J Exp Med. 1993 Nov 1;178(5):1693-700. doi: 10.1084/jem.178.5.1693.
Zotero 插件