一种从虎眼万年青鳞茎中提取的新型细胞毒性胆甾烷双糖链皂苷。

A new cytotoxic cholestane bisdesmoside from Ornithogalum saundersiae bulbs.

作者信息

Mimaki Y, Kuroda M, Kameyama A, Sashida Y, Hirano T, Oka K, Koike K, Nikaido T

机构信息

School of Pharmacy, Tokyo University of Pharmacy and Life Science, Japan.

出版信息

Biosci Biotechnol Biochem. 1996 Jun;60(6):1049-50. doi: 10.1271/bbb.60.1049.

DOI:10.1271/bbb.60.1049

PMID:8695908

Abstract

Bioassay-guided fractionation of the MeOH extract of Ornithogalum saundersiae bulbs led to the isolation of a new cholestane bisdesmoside with potent cytotoxic activities toward leukemia HL-60 and MOLT-4 cells. The structure was deduced mainly from spectroscopic information.

摘要

对虎眼万年青鳞茎甲醇提取物进行生物活性导向的分离，得到了一种新的胆甾烷双糖苷，它对白血病HL-60和MOLT-4细胞具有较强的细胞毒活性。该结构主要通过光谱信息推导得出。