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逆行性记忆保留伴顺行性遗忘和广泛的认知缺陷。

Spared retrograde memory with anterograde amnesia and widespread cognitive deficits.

作者信息

Siegert R J, Warrington E K

机构信息

National Hospital for Neurology and Neurosurgery, London.

出版信息

Cortex. 1996 Mar;32(1):177-85. doi: 10.1016/s0010-9452(96)80026-8.

DOI:10.1016/s0010-9452(96)80026-8
PMID:8697748
Abstract

A case is described of a young male who suffered head injuries in a motor accident and subsequently displayed a severe anterograde amnesia in the presence of a relatively intact retrograde memory. He also demonstrated marked impairment of general intellectual ability, naming, perceptual skills and executive functioning. This case demonstrates a striking dissociation between anterograde and retrograde memory. Moreover the retention of retrograde memory in the face of such severe and global cognitive impairment accentuates the dissociation or isolability of retrograde memory. It is further argued that while frontal impairment occurred in this case it lacks any of the hallmarks of frontal amnesia. The case is further evidence for the fractionation of amnesic syndromes.

摘要

本文描述了一名年轻男性的病例,他在一次车祸中头部受伤,随后出现了严重的顺行性遗忘,而逆行性记忆相对完好。他还表现出一般智力能力、命名、感知技能和执行功能的明显受损。该病例显示了顺行性记忆和逆行性记忆之间的显著分离。此外,在如此严重和全面的认知障碍情况下逆行性记忆的保留加剧了逆行性记忆的分离或可分离性。进一步认为,虽然该病例存在额叶损伤,但缺乏额叶遗忘症的任何特征。该病例进一步证明了遗忘综合征的细分。

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引用本文的文献

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Quantitative properties of the creation and activation of a cell-intrinsic duration-encoding engram.细胞内在持续时间编码记忆痕迹的形成与激活的定量特性。
Front Comput Neurosci. 2022 Nov 3;16:1019812. doi: 10.3389/fncom.2022.1019812. eCollection 2022.
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Consolidation theory and retrograde amnesia in humans.人类的巩固理论与逆行性失忆
Psychon Bull Rev. 2002 Sep;9(3):403-25. doi: 10.3758/bf03196300.
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Studies of retrograde memory: a long-term view.逆行性记忆研究:长期视角
Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13523-6. doi: 10.1073/pnas.93.24.13523.