Wilson G S, McCreary R, Kean J, Baxter J C
Pediatrics. 1979 Jan;63(1):135-41.
Disturbances of growth and behavior in infants and toddlers of women addicted to heroin during pregnancy have been reported in uncontrolled studies. In this study, 3- to 6-year-old children of heroin-addicted mothers were compared to three other groups matched for age, race, sex, birth weight, and socioeconomic status. Heroin-exposed children weighed less and were shorter than those in the comparison groups; 14% had a head circumference below the third percentile. Heroin-exposed children were rated by parents as less well adjusted than control children and they differed significantly in perceptual measures and on subtests of the Illinois Test of Psycholinguistic Abilities and McCarthy Scales of Children's Abilities relating to the process of organization. These findings suggest that chronic intrauterine exposure to heroin may affect growth and behavior as well as perceptual and learning processes in preschool children.
在非对照研究中,已有报告指出孕期吸食海洛因的女性所生婴幼儿存在生长和行为障碍。在本研究中,将海洛因成瘾母亲所生3至6岁儿童与另外三组在年龄、种族、性别、出生体重和社会经济地位方面相匹配的儿童进行了比较。接触过海洛因的儿童体重较轻,身高也低于对照组儿童;14%的儿童头围低于第三百分位。父母对接触过海洛因的儿童的适应能力评价低于对照儿童,并且在感知测量以及伊利诺伊心理语言能力测试和麦卡锡儿童能力量表中与组织过程相关的子测试中,他们存在显著差异。这些发现表明,孕期长期接触海洛因可能会影响学龄前儿童的生长、行为以及感知和学习过程。