Reháková M, Bakos D, Vizárová K, Soldán M, Jurícková M
Slovak Technical University, Faculty of Chemical Technology, Bratislava, Slovak Republic.
J Biomed Mater Res. 1996 Mar;30(3):369-72. doi: 10.1002/(SICI)1097-4636(199603)30:3<369::AID-JBM11>3.0.CO;2-F.
This article describes properties of composites of collagen-hyaluronic acid shaped to layered materials. According to the results, interactions of these two polymers are very strong. The properties can be influenced by chemical crosslinking using glyoxal and starch dialdehyde. The different behavior during enzymatic degradation by collagenase and in swelling experiments is discussed in relation to material composition. The valuable properties of the composites observed in this study show the possibility of their use as biomaterials.
本文描述了制成层状材料的胶原蛋白-透明质酸复合材料的特性。根据结果，这两种聚合物之间的相互作用非常强烈。其特性可通过使用乙二醛和淀粉二醛进行化学交联来影响。结合材料组成讨论了在胶原酶进行酶促降解过程中和溶胀实验中的不同行为。本研究中观察到的复合材料的宝贵特性表明了其用作生物材料的可能性。
