牛肝脏中胆汁酸与牛磺酸和甘氨酸结合的酶的动力学研究。
Kinetic studies on the enzymes conjugating bile acids with taurine and glycine in bovine liver.
作者信息
Vessey D A, Crissey M H, Zakim D
出版信息
Biochem J. 1977 Apr 1;163(1):181-3. doi: 10.1042/bj1630181.
Abstract
Synthesis of glyco- or tauro-cholate from choloyl-CoA and the respective amino acid is shown to be catalysed by the soluble fraction of liver cells. Kinetic evidence supports the conclusion that there are separate enzymes for the synthesis of glycocholate and taurocholate. The kinetic parameters of these enzymes were determined.
摘要
从胆酰辅酶A和相应氨基酸合成甘氨胆酸或牛磺胆酸的过程被证明是由肝细胞的可溶性部分催化的。动力学证据支持这样的结论，即存在分别用于合成甘氨胆酸和牛磺胆酸的酶。测定了这些酶的动力学参数。
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