Gentile V G, Isaacson G
Department of Otolaryngology/Bronchoesophagology, Temple University School of Medicine, Philadelphia, PA, USA.
Laryngoscope. 1996 Aug;106(8):1005-9. doi: 10.1097/00005537-199608000-00018.
It has been pediatric dogma that most children with cystic fibrosis (CF) have pansinusitis and few are symptomatic. To reassess this premise, we compared symptoms, clinical examinations, radiographic and surgical findings, and results of treatment in 19 children with cystic fibrosis who had undergone computed tomography at St. Christopher's Hospital (Philadelphia) from 1991 to 1994. We found two distinct patterns of sinus disease: chronic sinusitis (n = 3) and polyposis (n = 12). Two of the patients with polyposis had ethmoid mucoceles and 1 child had no sinus disease at all. Children with chronic sinusitis had headache as a major complaint, while those with polyposis suffered nasal obstruction alone unless a mucocele was present. Surgery provided marked and lasting improvement in the 14 patients who were operated on.
小儿医学的传统观念认为，大多数患有囊性纤维化（CF）的儿童都有全鼻窦炎，且很少有症状。为了重新评估这一前提，我们比较了1991年至1994年在圣克里斯托弗医院（费城）接受计算机断层扫描的19名囊性纤维化儿童的症状、临床检查、影像学和手术结果以及治疗结果。我们发现了两种不同的鼻窦疾病模式：慢性鼻窦炎（n = 3）和息肉病（n = 12）。两名息肉病患者患有筛窦黏液囊肿，1名儿童根本没有鼻窦疾病。慢性鼻窦炎患儿的主要症状是头痛，而息肉病患儿除非有黏液囊肿，否则仅遭受鼻塞。手术使接受手术的14名患者有了显著且持久的改善。
