Akisü M, Mir S, Genç B, Cura A
Department of Pediatrics, Ege University Faculty of Medicine, Bornova, Izmir.
Turk J Pediatr. 1996 Apr-Jun;38(2):223-5.
Thinner which contains aromatic hydrocarbons such as xylene, toluene and N-hexane is widely used in industrial plants manufacturing dyes, plastic, varnishes and glues. Chronic intoxication due to abuse of solvents, including thinner, by workers who inhale the solvent vapor is frequently encountered. Acute intoxication with ingestion of excessive amounts is relatively rare and usually fatal. It is reported that 45-50 ml of orally ingested thinner is enough to cause severe complications. The case reported here was forced to drink 200 ml of thinner by an older friend, and presented with severe complications such as rhabdomyolysis, polyneuropathy, chemical pneumonia and coma. To the best of our knowledge this is the first case reported in the literature to survive acute thinner intoxication with such complications.
含有二甲苯、甲苯和正己烷等芳烃的稀释剂广泛应用于制造染料、塑料、清漆和胶水的工厂。在吸入溶剂蒸气的工人中,因滥用包括稀释剂在内的溶剂而导致的慢性中毒屡见不鲜。过量摄入导致的急性中毒相对少见,且通常是致命的。据报道,口服45 - 50毫升稀释剂就足以引发严重并发症。此处报告的病例被一位年长的朋友强迫喝下200毫升稀释剂,并出现了横纹肌溶解、多发性神经病、化学性肺炎和昏迷等严重并发症。据我们所知,这是文献中报道的首例患有此类并发症且急性稀释剂中毒后存活的病例。