一种与罗克福青霉降解PR毒素相关的新型次级代谢产物。
A novel secondary metabolite relative to the degradation of PR toxin by Penicillium roqueforti.
作者信息
Chang S C, Yeh S F, Li S Y, Lei W Y, Chen M Y
机构信息
Institute of Biochemistry, National Yang-Ming University, Taiwan, Republic of China.
出版信息
Curr Microbiol. 1996 Mar;32(3):141-6. doi: 10.1007/s002849900025.
A secondary metabolite different from PR-imine and PR-amide was produced in the liquid (YESC) and solid (buckwheat) culture medium of Penicillium roqueforti. We isolated and purified the compound in pure and colorless crystalline form. On the basis of elemental analysis, mass, 1H and 13C nuclear magnetic resonance, infrared, and UV spectroscopy, the compound was identified as PR-acid (C17H20O7). The structures of PR-acid and PR toxin (C17H20O6) are closely related. Moreover, we discovered that PR-acid disappeared concurrently with the PR toxin in the culture medium. Thus, we postulate that PR toxin is degraded to PR-acid in the culture of P. roqueforti.
在罗克福青霉的液体（YESC）和固体（荞麦）培养基中产生了一种不同于PR-亚胺和PR-酰胺的次生代谢产物。我们将该化合物分离并纯化，得到了纯净的无色晶体形式。基于元素分析、质谱、1H和13C核磁共振、红外光谱和紫外光谱，该化合物被鉴定为PR-酸（C17H20O7）。PR-酸和PR毒素（C17H20O6）的结构密切相关。此外，我们发现PR-酸在培养基中与PR毒素同时消失。因此，我们推测在罗克福青霉培养过程中PR毒素降解为PR-酸。
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