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体外冲击波碎石术后尿结石的复发率及危险因素

Recurrence rate and risk factors for urinary calculi after extracorporeal shock wave lithotripsy.

作者信息

Sun B Y, Lee Y H, Jiaan B P, Chen K K, Chang L S, Chen K T

机构信息

Department of Surgery, Veterans General Hospital-Kaohsiung, Republic of China.

出版信息

J Urol. 1996 Sep;156(3):903-5; discussion 906.

PMID:8709359
Abstract

PURPOSE

We determined the recurrence rate after extracorporeal shock wave lithotripsy (ESWL*) and evaluated its associated risk factors, such as patient sex and age, volume of daily water intake, related diseases, family history of urinary calculi, number, burden and location of stones, residual stones after ESWL, serum uric acid level before ESWL and so forth.

MATERIALS AND METHODS

We conducted a retrospective study of 841 patients who underwent ESWL for primary treatment of urinary calculi between 1985 and 1987. Charts were reviewed for stone characteristics, outcomes and associated laboratory data. Followup 6 to 9 years later was done by mail and telephone interviews.

RESULTS

Followup data were available for 436 patients (52%). Overall, stones recurred in 51% of the 436 patients at a mean followup of 7.1 years. Late recurrences were common, and were noted in as many as 70% of the patients after 9 years. This rate is greater than what has been previously reported after other treatments. Cox regression analysis indicated that the major risk factors associated with recurrence were male gender (relative risk 1.406, p < 0.05) and multiple stones (relative risk 1.777, p < 0.05).

CONCLUSIONS

The frequent late recurrences support the speculation that ESWL might lead to greater recurrence rates. Therefore, the cost-effectiveness of ESWL versus other modalities for stone removal warrants more long-term evaluation.

摘要

目的

我们测定了体外冲击波碎石术(ESWL*)后的复发率,并评估了其相关危险因素,如患者性别和年龄、每日饮水量、相关疾病、尿路结石家族史、结石数量、负荷及位置、ESWL术后残余结石、ESWL术前血清尿酸水平等。

材料与方法

我们对1985年至1987年间接受ESWL初次治疗尿路结石的841例患者进行了一项回顾性研究。查阅病历以获取结石特征、治疗结果及相关实验室数据。6至9年后通过邮件和电话访谈进行随访。

结果

436例患者(52%)有随访数据。总体而言,436例患者中有51%在平均7.1年的随访中结石复发。晚期复发很常见,9年后多达70%的患者出现复发。该复发率高于此前其他治疗方法后的报道。Cox回归分析表明,与复发相关的主要危险因素为男性(相对风险1.406,p<0.05)和多发结石(相对风险1.777,p<0.05)。

结论

频繁的晚期复发支持了ESWL可能导致更高复发率的推测。因此,ESWL与其他结石清除方式相比的成本效益值得进行更多长期评估。

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