Kamihira O, Ono Y, Katoh N, Yamada S, Mizutani K, Ohshima S
Department of Urology, Komaki Shimin Hospital, Aichi, Japan.
J Urol. 1996 Oct;156(4):1267-71.
We followed patients who were stone-free after extracorporeal shock wave lithotripsy (ESWL) to investigate the factors that contributed to recurrent calculi.
For longer than 5 years 903 patients without residual fragments 3 months after ESWL were enrolled in this study. Plain abdominal films and/or excretory urograms were evaluated every 6 months for recurrent stones on the side of ESWL. Patients who presented with colic pain or other complaints and who were suspected of having recurrent stones were also examined. Stone recurrence rates were calculated with the Kaplan-Meier method. We assessed the influence of patient age; size, location, composition and configuration of the original stones, and pyuria after ESWL on stone recurrence.
Mean followup was 25 months and stones recurred in 183 of 903 renal units (20.3%). Kaplan-Meier recurrence rates were 6.7, 28.0 and 41.8% after 1, 3 and 5 years, respectively. There was a significant correlation between stone recurrence and multiple stones on one hand, and pyuria after ESWL on the other hand. Stones recurred most frequently in the lower calix. Recurrent stones were passed without intervention in 33 cases, while ESWL was repeated in 53.
These data demonstrate the importance of long-term followup and the search for an effective prophylactic therapy to prevent recurrence.
我们对体外冲击波碎石术(ESWL)后结石清除的患者进行随访,以研究导致结石复发的因素。
903例ESWL术后3个月无残余碎片的患者纳入本研究,随访时间超过5年。每隔6个月对ESWL侧进行腹部平片和/或排泄性尿路造影检查,以评估是否复发结石。对出现绞痛或其他症状且怀疑有结石复发的患者也进行检查。采用Kaplan-Meier法计算结石复发率。我们评估了患者年龄、原结石的大小、位置、成分和形态以及ESWL后脓尿对结石复发的影响。
平均随访25个月,903个肾单位中有183个(20.3%)复发结石。1年、3年和5年后的Kaplan-Meier复发率分别为6.7%、28.0%和41.8%。结石复发与多发结石以及ESWL后脓尿之间存在显著相关性。结石最常复发于下盏。33例复发结石未经干预自行排出,53例再次进行了ESWL。
这些数据表明长期随访以及寻找有效的预防治疗以防止复发的重要性。