Riordan-Eva P, Faldon M, Büttner-Ennever J A, Gass A, Bronstein A M, Gresty M A
Neuro-Otology Section, MRC Human Movement and Balance Unit, Institute of Neurology, London, UK.
Neurology. 1996 Jul;47(1):201-7. doi: 10.1212/wnl.47.1.201.
In a patient with a unilateral rostral midbrain lesion, three-dimensional scleral search coil eye movement recordings demonstrated slowing of ipsidirectional torsional fast phase eye movements without any abnormalities of torsional slow phases. On high-resolution MRI, the brainstem lesion localized to the area of the efferent pathways from the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF). This supports the experimental finding that unilateral inactivation of the riMLF results in a loss of ipsidirectional torsional fast phase eye movements and the hypothesis that there is lateralization of function throughout the torsional fast eye movement generating system.
在一名患有单侧中脑喙部病变的患者中，三维巩膜搜索线圈眼动记录显示同侧扭转性快速相眼动减慢，而扭转性慢相无任何异常。在高分辨率MRI上，脑干病变定位于内侧纵束喙间质核（riMLF）传出通路区域。这支持了riMLF单侧失活导致同侧扭转性快速相眼动丧失的实验发现，以及整个扭转性快速眼动产生系统存在功能侧化的假说。
