1983年至1988年纽约州先天性畸形婴儿的死亡率
Mortality among infants with congenital malformations, New York State, 1983 to 1988.
作者信息
Druschel C, Hughes J P, Olsen C
机构信息
Congenital Malformations Registry, New York State Department of Health, Albany 12203, USA.
出版信息
Public Health Rep. 1996 Jul-Aug;111(4):359-65.
OBJECTIVE
The authors examined first-year mortality and risk factors for mortality among infants with major congenital malformations.
METHODS
Infants with major congenital malformations born from 1983 to 1988 were identified from a statewide population-based congenital malformations registry. Variables analyzed included year of birth, birth weight, gestational age, infant sex, number of malformations, number of organ systems involved, level of care of the birth hospital, maternal age, maternal education, and maternal ethnicity.
RESULTS
Infants with major malformations had a risk of death 6.3 times higher than the general population of live births. The risk declined from 6.5 in 1983 to 5.9 in 1988. Birth weight and number of malformations were the strongest risk factors. The likelihood of survival was similar for white and black infants.
CONCLUSIONS
Being born with a malformation outweighs most of the other risks for infant mortality. Children with congenital malformations had higher cause-specific mortality for all causes except injury.
目的
作者研究了患有严重先天性畸形婴儿的第一年死亡率及死亡风险因素。
方法
从全州基于人群的先天性畸形登记处识别出1983年至1988年出生的患有严重先天性畸形的婴儿。分析的变量包括出生年份、出生体重、胎龄、婴儿性别、畸形数量、涉及的器官系统数量、出生医院的护理水平、母亲年龄、母亲教育程度和母亲种族。
结果
患有严重畸形的婴儿死亡风险比活产婴儿总体人群高6.3倍。该风险从1983年的6.5降至1988年的5.9。出生体重和畸形数量是最强的风险因素。白人和黑人婴儿的存活可能性相似。
结论
出生时患有畸形超过了婴儿死亡的大多数其他风险。除伤害外，先天性畸形儿童因所有原因导致的特定病因死亡率更高。
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