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[全髋关节置换术后关节周围骨化的补充信息(作者译)]

[Additional information regarding periarticular ossifications after total hip replacement (author's transl)].

作者信息

Eggert A, Seidel H, Ruhnke J

出版信息

Arch Orthop Unfallchir. 1977 Mar 31;87(3):343-8. doi: 10.1007/BF00416010.

Abstract

Residual monomer originating from acrylic bone cement is not the origin of periarticular calcifications after hip joint replacement. This has been demonstrated by gaschromatografic detection of monomeric methylmethacrylate in the liquid of the joint space. Up to 200 microng/ml monomeric MMA could be demonstrated in the first days after the operation only. The concentration of residual monomeric MMA in the bone cement is 1% to 4%. It is deminished time dependently by diffusion of the molecule in the surrounding tissue. All determined concentrations of monomeric MMA in the joint liquid are below the toxic range for tissue demage.

摘要

髋关节置换术后,源于丙烯酸骨水泥的残留单体并非关节周围钙化的根源。这已通过气相色谱法检测关节腔液体中的甲基丙烯酸甲酯单体得到证实。仅在术后头几天可检测到高达200微克/毫升的单体甲基丙烯酸甲酯。骨水泥中残留单体甲基丙烯酸甲酯的浓度为1%至4%。其浓度会因分子在周围组织中的扩散而随时间降低。关节液中所有测定的单体甲基丙烯酸甲酯浓度均低于组织损伤的毒性范围。

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