前列腺素、前列腺素代谢产物及花生四烯酸未能诱导人多形核白细胞的趋化作用。
Failure of prostaglandins, prostaglandin metabolites and arachidonic acid to elicit chemotaxis of human polymorphonuclear leukocytes.
作者信息
Pazzaglia A, Barker A, Warin A P, Greaves M W
出版信息
Br J Dermatol. 1977 May;96(5):533-6. doi: 10.1111/j.1365-2133.1977.tb07157.x.
Abstract
This paper reports chemotactic studies on human polymorphonuclear leukocytes using prostaglandins, prostaglandin precursors and prostaglandin metabolites in vitro. Chemotaxis could not be demonstrated when arachidonic acid, prostaglandins D2, E1, E2, F2alpha, and the prostaglandin metabolites 15 keto E2, 15 keto F2alpha were incubated with polymorphonuclear leukocytes using the Boyden millipore technique.
摘要
本文报道了在体外使用前列腺素、前列腺素前体和前列腺素代谢物对人多形核白细胞进行趋化性研究的结果。当使用博伊登微孔技术将花生四烯酸、前列腺素D2、E1、E2、F2α以及前列腺素代谢物15-酮基-E2、15-酮基-F2α与人多形核白细胞一起孵育时，未显示出趋化性。
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Failure of prostaglandins, prostaglandin metabolites and arachidonic acid to elicit chemotaxis of human polymorphonuclear leukocytes.前列腺素、前列腺素代谢产物及花生四烯酸未能诱导人多形核白细胞的趋化作用。
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