Miró E, Mirelis B, Navarro F, Prats G
Servicio de Microbiología, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona.
Enferm Infecc Microbiol Clin. 1996 Jan;14(1):31-3.
To study the emergence of amoxicilline/clavulanate resistance in Salmonella and Shigella.
We have studied 118 strains of Salmonella enterica and 11 strains of Shigella flexneri isolated in our laboratory along 1993. The MICs values for amoxicilline/clavulanate were determined by the E-Test method and confirmed by the standard agar dilution method.
We have observed that 6% (7 out of 118 strains) of Salmonella enterica and 42% (5 out of 11 strains) of Shigella flexneri isolates exhibited an intermediate susceptibility or were resistant to amoxicilline/clavulanate with MICs values ranging between 16 mg/l and 32 mg/l.
Along 1993 we have detected the emergence of an amoxicilline/clavulanate resistance in salmonellae and shigellae strains. To our knowledge this fact has not been published up to now (Medline, 1990-October 1994). We don't know the clinical importance of this fact.
研究沙门氏菌和志贺氏菌中阿莫西林/克拉维酸耐药性的出现情况。
我们研究了1993年在我们实验室分离出的118株肠炎沙门氏菌和11株福氏志贺氏菌。通过E-Test法测定阿莫西林/克拉维酸的MIC值，并通过标准琼脂稀释法进行确认。
我们观察到，6%（118株中的7株）的肠炎沙门氏菌和42%（11株中的5株）的福氏志贺氏菌分离株表现出中度敏感性或对阿莫西林/克拉维酸耐药，MIC值在16毫克/升至32毫克/升之间。
在1993年，我们检测到沙门氏菌和志贺氏菌菌株中出现了阿莫西林/克拉维酸耐药性。据我们所知，这一事实至今尚未发表（医学索引，1990年 - 1994年10月）。我们尚不清楚这一事实的临床重要性。
