Lee F I, Harry D S, Adams W G, Litchfield M
Br J Ind Med. 1977 May;34(2):142-7. doi: 10.1136/oem.34.2.142.
Following the occurrence of hepatic fibrosis and angiosarcoma in polyvinyl chloride autoclave workers, a screening programme was set up for workers at risk in a large production plant. There was no significant difference in liver function tests between workers and a control group of men in the same factory, not exposed to vinyl chloride. Four exposed workers out of 422 were found to have enlarged spleens compared with none out of 202 controls. Liver biopsies from selected cases showed no significant pathological changes, although there was minimal increase in portal tract and sinusoidal fibrosis in exposed workers.
在聚氯乙烯高压釜工人中出现肝纤维化和血管肉瘤后，为一家大型生产厂的高危工人设立了筛查项目。与同一工厂未接触氯乙烯的男性对照组相比，工人的肝功能测试没有显著差异。422名接触工人中有4人脾脏肿大，而202名对照组中无人脾脏肿大。尽管接触工人的门管区和窦状隙纤维化略有增加，但所选病例的肝活检未显示明显病理变化。
