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氯乙烯工人的肝病筛查。

Screening for liver disease in vinyl chloride workers.

作者信息

Lee F I, Harry D S, Adams W G, Litchfield M

出版信息

Br J Ind Med. 1977 May;34(2):142-7. doi: 10.1136/oem.34.2.142.

Abstract

Following the occurrence of hepatic fibrosis and angiosarcoma in polyvinyl chloride autoclave workers, a screening programme was set up for workers at risk in a large production plant. There was no significant difference in liver function tests between workers and a control group of men in the same factory, not exposed to vinyl chloride. Four exposed workers out of 422 were found to have enlarged spleens compared with none out of 202 controls. Liver biopsies from selected cases showed no significant pathological changes, although there was minimal increase in portal tract and sinusoidal fibrosis in exposed workers.

摘要

在聚氯乙烯高压釜工人中出现肝纤维化和血管肉瘤后,为一家大型生产厂的高危工人设立了筛查项目。与同一工厂未接触氯乙烯的男性对照组相比,工人的肝功能测试没有显著差异。422名接触工人中有4人脾脏肿大,而202名对照组中无人脾脏肿大。尽管接触工人的门管区和窦状隙纤维化略有增加,但所选病例的肝活检未显示明显病理变化。

相似文献

1
Screening for liver disease in vinyl chloride workers.氯乙烯工人的肝病筛查。
Br J Ind Med. 1977 May;34(2):142-7. doi: 10.1136/oem.34.2.142.
2
Medical surveillance of vinyl chloride workers.氯乙烯工人的医学监测。
Proc R Soc Med. 1976 Apr;69(4):307-9. doi: 10.1177/003591577606900428.
4
Vinyl chloride-associated liver disease.氯乙烯相关肝病
Ann Intern Med. 1976 Jun;84(6):717-31. doi: 10.7326/0003-4819-84-6-717.
5
Clinical and morphologic features of hepatic angiosarcoma in vinyl chloride workers.氯乙烯作业工人肝血管肉瘤的临床及形态学特征
Cancer. 1976 Jan;37(1):149-63. doi: 10.1002/1097-0142(197601)37:1<149::aid-cncr2820370122>3.0.co;2-7.

本文引用的文献

3
Brain scanning in children.
JAMA. 1967 Jul 3;201(1):83-5. doi: 10.1001/jama.201.1.83.
9
Angiosarcoma of the liver in a vinyl-chloride worker.一名氯乙烯工人患肝脏血管肉瘤。
Lancet. 1974 Jun 29;1(7870):1316-8. doi: 10.1016/s0140-6736(74)90683-7.
10
Vinyl chloride and the production of PVC.氯乙烯与聚氯乙烯的生产
Proc R Soc Med. 1976 Apr;69(4):277-81. doi: 10.1177/003591577606900417.

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