Schiffer J, Walach N, Nyska A, Lushkov G, Rothman S, Pollak L
Department of Neurosurgery and Oncology, Assaf Harofeh Medical Center, Zerifin, Israel.
Neurol Res. 1996 Feb;18(1):87-8. doi: 10.1080/01616412.1996.11740383.
The antitumoral effect of Cisplatinum is well known, including its effect on brain tumors. With the purpose of establishing the effect of intraarterial cis-dichlorodiammine platinum (CDDP) on the brain, Cisplatinum was injected in rabbits that were sacrificed at different intervals. The general clinical and neurological condition of the rabbits was unaffected, and histopathological examination of the rabbit's brain was normal.
顺铂的抗肿瘤作用是众所周知的，包括其对脑肿瘤的作用。为了确定动脉内注射顺式二氯二氨铂（CDDP）对大脑的影响，在不同时间间隔处死的兔子体内注射了顺铂。兔子的一般临床和神经状况未受影响，对兔子大脑的组织病理学检查结果正常。
