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[定量超声评估绝经后骨质疏松症。与双能X线吸收法的比较]

[Quantitative ultrasonography in the evaluation of postmenopausal osteoporosis. Comparison with dual energy x-ray absorptiometry].

作者信息

Magarò M, Zoli A, Caricchio R, Angelosante S, Mirone L, Altomonte L, Palazzoni G

机构信息

Istituto di Medicina Interna e Geriatria, Università Cattolica del Sacro Cuore di Roma.

出版信息

Ann Ital Med Int. 1995 Oct-Dec;10(4):218-21.

PMID:8718655
Abstract

In order to compare the capacities of quantitative ultrasonography and dual energy X-ray absorptiometry to measure bone mineral density (BMD) in postmenopausal women, 45 postmenopausal patients were studied. They were divided into two groups on the basis of the results of absorptiometry: Group A (20 patients) had BMD values within normal limits, and Group B (25 patients) had BMD values lower than 1 standard deviation (SD) of the average for an age and sex matched population. Ultrasonography of the non-dominant heel was carried out on both groups to determine broadband ultrasound attenuation (BUA), speed of sound (SOS) and bone velocity (BV). A negative correlation between age and BMD, BV, SOS, and BUA was observed in all subjects. A positive correlation between BMD and BV and between BMD and SOS was found. In Group A, age correlated negatively with BMD, BUA, SOS and BV, and BMD correlated positively with BV. In Group B, age correlated negatively with BMD, and BMD correlated positively with BV and SOS. BV values were significantly elevated in Group B. The study evidenced a relationship between ultrasonography and absorptiometry in determining bone density in postmenopausal women. As ultrasonography and absorptiometry provided comparable information on bone density, we point out that ultrasonography can be used as a simple and sensitive indicator for postmenopausal osteoporosis.

摘要

为比较定量超声检查和双能X线吸收法测量绝经后女性骨密度(BMD)的能力,对45例绝经后患者进行了研究。根据吸收法结果将她们分为两组:A组(20例患者)骨密度值在正常范围内,B组(25例患者)骨密度值低于年龄和性别匹配人群平均值的1个标准差(SD)。对两组均进行非优势足跟的超声检查,以确定宽带超声衰减(BUA)、声速(SOS)和骨速度(BV)。在所有受试者中均观察到年龄与骨密度、骨速度、声速和宽带超声衰减呈负相关。发现骨密度与骨速度以及骨密度与声速呈正相关。在A组中,年龄与骨密度、宽带超声衰减、声速和骨速度呈负相关,骨密度与骨速度呈正相关。在B组中,年龄与骨密度呈负相关,骨密度与骨速度和声速呈正相关。B组的骨速度值显著升高。该研究证明了超声检查与吸收法在确定绝经后女性骨密度方面的关系。由于超声检查和吸收法在骨密度方面提供了可比的信息,我们指出超声检查可作为绝经后骨质疏松症的一种简单而敏感的指标。

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