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Molecular neurobiology and pharmacology of the vasopressin/oxytocin receptor family.血管升压素/催产素受体家族的分子神经生物学与药理学
Cell Mol Neurobiol. 1995 Oct;15(5):573-95. doi: 10.1007/BF02071318.
2
Vasopressin and oxytocin receptors.血管加压素和催产素受体。
Baillieres Clin Endocrinol Metab. 1996 Jan;10(1):75-96. doi: 10.1016/s0950-351x(96)80314-4.
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Vasopressin receptors: structural functional relationships and role in neural and endocrine regulation.
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Analysis of interactions responsible for vasopressin binding to human neurohypophyseal hormone receptors-molecular dynamics study of the activated receptor-vasopressin-G(alpha) systems.负责血管加压素与人神经垂体激素受体结合的相互作用分析——活化受体-血管加压素-G(α)系统的分子动力学研究
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Signal transduction pathways of the human V1-vascular, V2-renal, V3-pituitary vasopressin and oxytocin receptors.人类血管加压素和催产素受体的V1（血管）、V2（肾脏）、V3（垂体）信号转导通路。
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Vasopressin anti-idiotypic antibody staining in the rat brain: colocalization with [35S] [pGlu4, Cyt6]AVP(4-9) binding sites.
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Characterization of a novel, linear radioiodinated vasopressin antagonist: an excellent radioligand for vasopressin V1a receptors.一种新型线性放射性碘化血管加压素拮抗剂的表征：一种用于血管加压素V1a受体的优秀放射性配体。
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Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells.蛙皮素、血管加压素和内皮素可迅速刺激瑞士3T3细胞中黏着斑相关蛋白桩蛋白的酪氨酸磷酸化。
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Molecular cloning and functional characterization of V2 [8-lysine] vasopressin and oxytocin receptors from a pig kidney cell line.来自猪肾细胞系的V2 [8-赖氨酸]血管加压素和催产素受体的分子克隆及功能特性分析
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Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors.SR 49059的生化和药理学特性，一种新型、强效、非肽类大鼠和人类血管加压素V1a受体拮抗剂。
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Direct evidence for tyrosine and threonine phosphorylation and activation of mitogen-activated protein kinase by vasopressin in cultured rat vascular smooth muscle cells.血管加压素在培养的大鼠血管平滑肌细胞中使丝裂原活化蛋白激酶酪氨酸和苏氨酸磷酸化并激活的直接证据。
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Design, synthesis and some uses of receptor-specific agonists and antagonists of vasopressin and oxytocin.血管加压素和催产素受体特异性激动剂及拮抗剂的设计、合成与一些用途。
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Vasopressin-induction of cyclic AMP in cultured hippocampal neurons.
Brain Res Dev Brain Res. 1993 Jan 15;71(1):101-5. doi: 10.1016/0165-3806(93)90110-v.

血管升压素/催产素受体家族的分子神经生物学与药理学

Molecular neurobiology and pharmacology of the vasopressin/oxytocin receptor family.

作者信息

Peter J, Burbach H, Adan R A, Lolait S J, van Leeuwen F W, Mezey E, Palkovits M, Barberis C

机构信息

Department of Medical Pharmacology, Utrecht University, Netherlands.

出版信息

Cell Mol Neurobiol. 1995 Oct;15(5):573-95. doi: 10.1007/BF02071318.

DOI:10.1007/BF02071318
PMID:8719042
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11563090/
Abstract
  1. VP and OT mediate their wealth of effects via 4 receptor subtypes V1a, V1b, V2, and OT receptors. 2. We here review recent insights in the pharmacological properties, structure activity relationships, species differences in ligand specificity, expression patterns, and signal transduction of VP/OT receptor. 3. Furthermore, the existence of additional VP/OT receptor subtypes is discussed.
摘要
  1. 血管加压素（VP）和催产素（OT）通过4种受体亚型V1a、V1b、V2和OT受体介导它们丰富多样的效应。2. 在此，我们综述了关于VP/OT受体的药理特性、构效关系、配体特异性的物种差异、表达模式及信号转导的最新见解。3. 此外，还讨论了是否存在其他VP/OT受体亚型。