Hayes H M, Fraumeni J F
Cancer Res. 1977 Aug;37(8 Pt 1):2553-6.
A retrospective study of medical records from 13 veterinary university hospitals and clinics yielded 73 cases of confirmed primary neoplasms of the kidney and renal pelvis. Analysis of the 34 cases of renal carcinoma revealed no evidence of familial (breed) predisposition, but an excess risk was identified in males, especially during middle life. The morphological and epidemiological features of canine renal carcinoma are similar to those of renal carcinoma in humans. The dog may be a suitable model for further research into the causes of this cancer.
一项对13家兽医大学医院和诊所病历的回顾性研究发现了73例确诊的原发性肾和肾盂肿瘤病例。对34例肾癌病例的分析显示，没有证据表明存在家族性（品种）易感性，但在雄性中发现了较高的风险，尤其是在中年时期。犬类肾癌的形态学和流行病学特征与人类肾癌相似。狗可能是进一步研究这种癌症病因的合适模型。
