Petti S, Pezzi R
Hygiene Institute, La Sapienza University of Rome, Italy.
New Microbiol. 1996 Apr;19(2):133-40.
The aim of the present paper was to study whether sucrose consumption may affect the level of salivary Streptococcus mutans. The study was justified by the disagreement between results of "in vitro", animal and human experiments and results of epidemiological studies made on study-populations. According to experimental research, sucrose availability promotes Streptococcus mutans selection and development in the oral cavity. On the other hand, the results of epidemiological studies run counter to these experiments. In the present study, the main reasons for this disagreement were investigated and identified. From this, an epidemiological study was performed, taking into account these potentially confounding factors. The results show that sucrose consumption is actually able to promote Streptococcus mutans selection and development in the oral cavity, thus increasing the risk of dental caries.
本文的目的是研究蔗糖摄入是否会影响唾液中变形链球菌的水平。“体外”、动物和人体实验的结果与针对研究人群进行的流行病学研究结果之间存在分歧，这使得该研究具有合理性。根据实验研究，蔗糖的可获得性会促进口腔中变形链球菌的选择和生长。另一方面，流行病学研究的结果与这些实验结果相反。在本研究中，对这种分歧的主要原因进行了调查和确定。据此，在考虑这些潜在混杂因素的情况下进行了一项流行病学研究。结果表明，蔗糖摄入实际上能够促进口腔中变形链球菌的选择和生长，从而增加患龋齿的风险。
