Hirota T, Tomida T, Iwasa M, Takahashi K, Kaneda M, Tamaki H
Department of Surgery, Mie Prefectural Hospital of Shima, Japan.
Int J Pancreatol. 1996 Apr;19(2):145-53. doi: 10.1007/BF02805229.
Pancreatic metastasis from renal cell carcinoma is extremely rare. The average time between nephrectomy and the diagnosis of metachronous metastases is reported to exceed 10 yr. Therefore, the initial diagnosis may be neglected in the cases of prolonged disease-free interval. When it does occur simultaneously or metachronously, aggressive surgical resection, when possible, seems to be the most effective treatment for this metastatic lesion.
An 81-yr-old female patient, who 8 yr previously had undergone right radical nephrectomy for renal cell carcinoma, presented with solitary pancreatic metastasis, which was successfully treated with a distal pancreatectomy. Only 66 cases of clinically diagnosed renal cell carcinoma metastatic to the pancreas are reported in the world literature and 49 of the patients (including ours) underwent a definitive surgical resection. Our case, treated by distal pancreatectomy, and a review of the relevant literature including all reported cases of renal cell carcinoma metastatic to the pancreas, are presented.
The patient was well without any evidence of recurrence at 22 mo after the operation.
肾细胞癌胰腺转移极为罕见。据报道，肾切除术后与异时性转移诊断之间的平均时间超过10年。因此，在无病间期延长的情况下，初始诊断可能被忽视。当同时或异时发生转移时，若有可能，积极的手术切除似乎是治疗这种转移性病变最有效的方法。
一名81岁女性患者，8年前因肾细胞癌接受了右根治性肾切除术，现出现孤立性胰腺转移，经远端胰腺切除术成功治疗。世界文献中仅报道了66例临床诊断为肾细胞癌转移至胰腺的病例，其中49例患者（包括我们的病例）接受了确定性手术切除。本文介绍了我们通过远端胰腺切除术治疗的病例，并对包括所有报道的肾细胞癌转移至胰腺病例在内的相关文献进行了综述。
患者术后22个月情况良好，无任何复发迹象。
