Koivusalo A, Mäkisalo H, Talja M, Siitonen A, Vuopio-Varkila J, Ruutu M, Höckerstedt K
Fourth Dept. of Surgery, Helsinki University of Central Hospital, Finland.
Scand J Gastroenterol. 1996 Apr;31(4):398-403. doi: 10.3109/00365529609006417.
T-tube-related bacteriobilia causes infectious complications and obstruction. To prevent these, the choice of T-tube material may be of importance.
Transected common bile ducts (CBDs) of 17 piglets were sutured over latex or silicone T-tubes, or without a T-tube.
After 6 weeks bacteriobilia was found in all of 12 CBDs with and in 1 of 5 CBDs without a T-tube (p < 0.05). By scanning electron microscopy (SEM) four of five latex and none of five silicone T-tubes had bacterial biofilms (p < 0.05). All tubes remained patent. Segments of T-tubes were incubated with five different bacterial strains. Sonication and SEM showed that 0.1-1.1% of 10(7) colony-forming units of inoculum adhered to T-tubes. Two to six times more bacteria adhered to latex than to silicone (p < 0.05).
Silicone offers better long-term patency than latex. Less infectious complications occur if T-tubes are omitted.
T管相关的胆系感染会导致感染性并发症和梗阻。为预防这些情况，T管材料的选择可能很重要。
将17只仔猪的胆总管横断后，分别缝合于乳胶或硅胶T管上，或不放置T管。
6周后，放置T管的12条胆总管中均发现胆系感染，未放置T管的5条胆总管中有1条出现胆系感染（p<0.05）。通过扫描电子显微镜（SEM）检查发现，5条乳胶T管中有4条有细菌生物膜形成，而5条硅胶T管中均未发现（p<0.05）。所有T管均保持通畅。将T管片段与5种不同细菌菌株一起培养。超声处理和SEM显示，接种物中10⁷ 个菌落形成单位中有0.1% - 1.1%附着于T管。附着于乳胶T管的细菌比附着于硅胶T管的细菌多2至6倍（p<0.05）。
硅胶T管比乳胶T管具有更好的长期通畅性。不放置T管时感染性并发症更少。
