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既往酗酒者的肺功能

Pulmonary function in former alcoholics.

作者信息

Emirgil C, Sobol B J

出版信息

Chest. 1977 Jul;72(1):45-51. doi: 10.1378/chest.72.1.45.

Abstract

Pulmonary function was evaluated in 44 former alcoholics (abstinence, 0.5 to 32 years) without cardiac or specific pulmonary disease. All were members of Alcoholics Anonymous. Fourteen subjects (32 percent) were non-smokers, ex-smokers, and cigar or pipe smokers, yet 28 subjects (64 percent) had abnormal expiratory flow rates, and 17 (39 percent) had an elevated value for the ratio of the residual volume to the total lung capacity. Single-breath diffusing capacity was abnormal in seven subjects (16 percent). Of interest was the high incidence (77 percent) of obstructive phenomena among the women. This high incidence of abnormalities among both the men and women could not be attributed to previous pulmonary infection or smoking. Comparison of these patients with chronic alcoholics suggests that the obstructive component in these patients is, in part, a result of their past alcoholic intake and that it is not reversed by abstinence. On the other hand, the impairment in diffusion, which was so common in alcoholics, appears to be reversible with sobriety.

摘要

对44名无心脏疾病或特定肺部疾病的既往酗酒者(戒酒时间为0.5至32年)进行了肺功能评估。他们均为戒酒互助会成员。14名受试者(32%)为不吸烟者、已戒烟者、雪茄或烟斗吸烟者,但28名受试者(64%)呼气流量率异常,17名(39%)残气量与肺总量之比升高。7名受试者(16%)单次呼吸弥散能力异常。有趣的是,女性中阻塞性现象的发生率很高(77%)。男性和女性中这种高异常发生率不能归因于既往肺部感染或吸烟。将这些患者与慢性酗酒者进行比较表明,这些患者的阻塞性成分部分是其过去饮酒的结果,且不会因戒酒而逆转。另一方面,酗酒者中常见的弥散功能损害似乎可随戒酒而恢复。

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