Shenefelt P D
Department of Internal Medicine, College of Medicine, University of South Florida, Tampa 33612, USA.
Cutis. 1996 May;57(5):315-9.
Pyoderma gangrenosum often presents a difficult therapeutic challenge. The case is described of a 42-year-old black man with the association of cystic acne, hidradenitis suppurativa, and seronegative arthritis with pyoderma gangrenosum. The pyoderma gangrenosum ulcers remained refractory to treatment until therapies aimed in part at the associated diseases were begun. Minocycline was given for treatment of cystic acne and hidradenitis suppurativa as well as pyoderma gangrenosum. Sulfasalazine was prescribed for seronegative arthritis as well as pyoderma gangrenosum. The combination therapy permitted healing of the pyoderma gangrenosum ulcers.
坏疽性脓皮病常常带来棘手的治疗难题。本文描述了一名42岁黑人男性，其患有囊性痤疮、化脓性汗腺炎、血清阴性关节炎并伴有坏疽性脓皮病。坏疽性脓皮病溃疡对治疗一直具有抵抗性，直到开始部分针对相关疾病的治疗。给予米诺环素治疗囊性痤疮、化脓性汗腺炎以及坏疽性脓皮病。给予柳氮磺胺吡啶治疗血清阴性关节炎以及坏疽性脓皮病。联合治疗使坏疽性脓皮病溃疡得以愈合。
