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欧洲共同体呼吸健康调查(ECRHS)中呼吸道症状患病率、自我报告的哮喘发作情况及哮喘药物使用情况的差异。

Variations in the prevalence of respiratory symptoms, self-reported asthma attacks, and use of asthma medication in the European Community Respiratory Health Survey (ECRHS).

出版信息

Eur Respir J. 1996 Apr;9(4):687-95. doi: 10.1183/09031936.96.09040687.

Abstract

Asthma is a common chronic disorder which may be increasing in prevalence. However, little is known of its distribution and determinants. The European Community Respiratory Health Survey (ECRHS) is a multicentre survey of the prevalence, determinants and management of asthma. This paper presents a descriptive account of the variation in self-reported attacks of asthma and asthma symptoms across Europe, and in part fulfils the first aim of the study. A screening questionnaire, including seven questions relating to the 12 month prevalence of symptoms of asthma, was distributed to representative samples of 20-44 year old men and women in 48 centers, predominantly in Western Europe. The median response rate to the questionnaire was 75% but, after removing from the denominator those who were the wrong age, were known to have moved out of the area, or had died, it was 78% (range 54-100). The prevalence of all symptoms varied widely. Although these were generally lower in northern, central and southern Europe and higher in the British Isles, New Zealand, Australia and the United States, there were wide variations even within some countries. Centres with a high prevalence of self-reported attacks of asthma also reported high prevalences of nasal allergies and of waking at night with breathlessness. The use of asthma medication was more common where wheeze and asthma attacks were more frequent. In most centres in The Netherlands, Sweden, New Zealand and the United Kingdom over 80% of those with a diagnosis of asthma were currently using asthma medication. In Italy, France and Spain the rate was generally less than 70%. These data are the best evidence to date that geographical differences in asthma prevalence exist, are substantial and are not an artefact of the use of noncomparable methods.

摘要

哮喘是一种常见的慢性疾病,其患病率可能正在上升。然而,对其分布和决定因素却知之甚少。欧洲共同体呼吸健康调查(ECRHS)是一项关于哮喘患病率、决定因素和管理的多中心调查。本文描述了欧洲各地自我报告的哮喘发作和哮喘症状的差异,部分实现了该研究的首要目标。一份筛查问卷,包括七个与哮喘症状12个月患病率相关的问题,被分发给48个中心的20 - 44岁男性和女性的代表性样本,这些中心主要位于西欧。问卷的中位回复率为75%,但在分母中剔除那些年龄不符、已知已搬离该地区或已去世的人后,回复率为78%(范围为54 - 100)。所有症状的患病率差异很大。尽管这些症状在北欧、中欧和南欧总体上较低,而在不列颠群岛、新西兰、澳大利亚和美国较高,但即使在一些国家内部也存在很大差异。自我报告哮喘发作患病率高的中心,鼻过敏和夜间因呼吸急促醒来的患病率也高。在喘息和哮喘发作更频繁的地方,使用哮喘药物更为普遍。在荷兰、瑞典、新西兰和英国的大多数中心,超过80%被诊断为哮喘的人目前正在使用哮喘药物。在意大利、法国和西班牙,这一比例通常低于70%。这些数据是迄今为止最好的证据,表明哮喘患病率存在地理差异,这种差异很大,且并非使用不可比方法造成的假象。

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