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口服色甘酸钠或低抗原饮食对特应性皮炎患儿的疗效评估:一项针对1085例患者的多中心研究。

Evaluation of the efficacy of oral cromolyn sodium or an oligoantigenic diet in children with atopic dermatitis: a multicenter study of 1085 patients.

作者信息

Businco L, Meglio P, Amato G, Balsamo V, Cainelli T, Cantone P, Castro M, Coletta A, Corrias A, Giorgi P L, Grazioli I, Longo-Papadia L, Marcucci F, Masi M, Pavesio D, Scotta S, Seidenari S, Vierucci A

机构信息

Ped. Dpt., La Sapienza University of Rome, Italy.

出版信息

J Investig Allergol Clin Immunol. 1996 Mar-Apr;6(2):103-9.

PMID:8727267
Abstract

One thousand eighty-five children with atopic dermatitis were enrolled in a multicenter study to evaluate the efficacy of 4 weeks of oral sodium cromoglycate or 4 weeks of a restricted diet. One thousand-eleven children (93%) concluded the study. At the end of the trial there was a significant improvement in skin lesions in the two groups: 61% of the patients in the sodium cromoglycate group and 69% in the restricted diet showed a significant improvement in atopic dermatitis. We concluded that, at least in our experimental design, both sodium cromoglycate and a restricted diet are equally effective in atopic dermatitis.

摘要

1085名患有特应性皮炎的儿童参与了一项多中心研究,以评估口服色甘酸钠4周或限制饮食4周的疗效。1011名儿童(93%)完成了该研究。试验结束时,两组的皮肤损伤均有显著改善:色甘酸钠组61%的患者和限制饮食组69%的患者的特应性皮炎有显著改善。我们得出结论,至少在我们的实验设计中,色甘酸钠和限制饮食在治疗特应性皮炎方面同样有效。

相似文献

1
Evaluation of the efficacy of oral cromolyn sodium or an oligoantigenic diet in children with atopic dermatitis: a multicenter study of 1085 patients.口服色甘酸钠或低抗原饮食对特应性皮炎患儿的疗效评估:一项针对1085例患者的多中心研究。
J Investig Allergol Clin Immunol. 1996 Mar-Apr;6(2):103-9.
2
Double-blind crossover trial with oral sodium cromoglycate in children with atopic dermatitis due to food allergy.食物过敏所致特应性皮炎患儿口服色甘酸钠的双盲交叉试验。
Ann Allergy. 1986 Dec;57(6):433-8.
3
Food allergy and atopic dermatitis in children: treatment with oral sodium cromoglycate.儿童食物过敏与特应性皮炎:口服色甘酸钠治疗
Ann Allergy. 1981 Sep;47(3):173-5.
4
[Treatment of atopic dermatitis with sodium cromoglycate in children not selected for food allergy].[色甘酸钠治疗未选择食物过敏儿童的特应性皮炎]
Minerva Pediatr. 1985 Mar 31;37(5-6):263-8.
5
Oral sodium cromoglycate treatment of atopic dermatitis related to food allergy.口服色甘酸钠治疗与食物过敏相关的特应性皮炎。
Allergy. 1984 Oct;39(7):535-41. doi: 10.1111/j.1398-9995.1984.tb00875.x.
6
[Atopic eczema: treatment by sodium cromoglycate].
Nouv Presse Med. 1979 Feb 10;8(7):530.
7
Atopic dermatitis due to food allergens.食物变应原所致特应性皮炎
Practitioner. 1981 Nov;225(1361):1657-60.
8
Intestinal permeability, atopic eczema and oral disodium cromoglycate.肠道通透性、特应性湿疹与口服色甘酸钠二钠
Pediatr Med Chir. 1991 Mar-Apr;13(2):169-72.
9
[Effect of disodium cromoglycate per os in atopic dermatitis].
Nouv Presse Med. 1979 Jun 16;8(27):2288.
10
The role of pharmacologic agents in the prevention or treatment of allergic food disorders.药物制剂在预防或治疗食物过敏症中的作用。
Ann Allergy. 1986 Jul;57(1):53-60.

引用本文的文献

1
Food Avoidance Diets for Dermatitis.用于治疗皮炎的食物回避饮食
Curr Allergy Asthma Rep. 2015 Oct;15(10):60. doi: 10.1007/s11882-015-0563-8.
2
Treatment of childhood eczema.儿童湿疹的治疗。
Paediatr Drugs. 2002;4(11):729-35. doi: 10.2165/00128072-200204110-00004.