Businco L, Meglio P, Amato G, Balsamo V, Cainelli T, Cantone P, Castro M, Coletta A, Corrias A, Giorgi P L, Grazioli I, Longo-Papadia L, Marcucci F, Masi M, Pavesio D, Scotta S, Seidenari S, Vierucci A
Ped. Dpt., La Sapienza University of Rome, Italy.
J Investig Allergol Clin Immunol. 1996 Mar-Apr;6(2):103-9.
One thousand eighty-five children with atopic dermatitis were enrolled in a multicenter study to evaluate the efficacy of 4 weeks of oral sodium cromoglycate or 4 weeks of a restricted diet. One thousand-eleven children (93%) concluded the study. At the end of the trial there was a significant improvement in skin lesions in the two groups: 61% of the patients in the sodium cromoglycate group and 69% in the restricted diet showed a significant improvement in atopic dermatitis. We concluded that, at least in our experimental design, both sodium cromoglycate and a restricted diet are equally effective in atopic dermatitis.
1085名患有特应性皮炎的儿童参与了一项多中心研究,以评估口服色甘酸钠4周或限制饮食4周的疗效。1011名儿童(93%)完成了该研究。试验结束时,两组的皮肤损伤均有显著改善:色甘酸钠组61%的患者和限制饮食组69%的患者的特应性皮炎有显著改善。我们得出结论,至少在我们的实验设计中,色甘酸钠和限制饮食在治疗特应性皮炎方面同样有效。