Long D M, BenDebba M, Torgerson W S, Boyd R J, Dawson E G, Hardy R W, Robertson J T, Sypert G W, Watts C
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.
J Spinal Disord. 1996 Feb;9(1):40-58.
Low back pain is an extremely common, seriously disabling, nonfatal public health problem worldwide. The National Low Back Pain Study was a multicenter study of a large, heterogeneous group of patients who have been referred to either a neurosurgeon or an orthopedic surgeon for the evaluation and treatment of a persistent complaint of low back pain. In this paper, we characterize persistent low back pain patients and their complaints, describe the impact of persistent low back pain on the patients' functional and psychological status, report on the patients' medical characteristics, and identify treatments that are currently prescribed for these patients. Persistent low back pain is most common among people in their mid-to-late thirties and early-to-mid forties. The patients are mostly white, well educated, and generally affluent. The majority are gainfully employed, but some quit working because of pain and those who do tend to be less educated, and more likely to be involved in litigation. The average patient has had low back pain intermittently for 10 years. The pain is usually well localized but its severity varies considerably. Besides pain, most persistent low back pain patients report a variety of motor and sensory deficits. Patients also report significant functional impairment at work, at play, and at home. The typical patient does not, however, display significant psychological distress. Most patients have consulted multiple health care providers, have received a variety of treatments, and have used a variety of medications to alleviate pain; a few have been subjected to more aggressive treatment measures including surgery, intradiscal therapy, and narcotic and psychoactive drugs. None of these treatments has been effective. Physical examinations of these patients do not provide significant clues for making a definitive diagnosis. Nonspecific abnormalities such as muscle spasm, tenderness, and trigger points are quite common, but motor weakness and sensory deficits in the lower extremities, and reflex changes in the knees and ankles, are much less common. The classic combination of reflex changes, motor weakness, and sensory deficits associated with specific protruded discs are extremely rare even though one of three patients had a diagnosis of disc herniation. Diagnostic imaging studies revealed that the majority of persistent low back pain patients have spondylotic abnormalities involving root compression or lumbar instability or both, with root compression as the primary cause of the complaint. Myofascial syndrome and lumbar instability were the next most common diagnoses. After a thorough evaluation by specialists in spinal disorders, three of five persistent low back pain patients were prescribed an additional course of conservative therapy, one of five was prescribed surgery, and the rest were prescribed no treatment. Persistent low back pain patients appear to be a distinct group of low back pain patients who are different from patients who have similar nonpersistent acute symptoms and those who have the chronic pain syndrome characterized by significant behavioral and psychological co-morbidities.
腰痛是全球范围内极为常见、严重致残且非致命的公共卫生问题。国家腰痛研究是一项针对大量异质性患者群体的多中心研究,这些患者因持续性腰痛的评估和治疗而被转诊至神经外科医生或骨科医生处。在本文中,我们对持续性腰痛患者及其症状进行了特征描述,阐述了持续性腰痛对患者功能和心理状态的影响,报告了患者的医学特征,并确定了目前为这些患者开具的治疗方法。持续性腰痛在三十五六岁至四十出头的人群中最为常见。患者大多为白人,受过良好教育,且普遍富裕。大多数人有工作收入,但有些人因疼痛而辞职,而这些辞职者往往受教育程度较低,且更有可能卷入诉讼。患者平均间歇性腰痛已达10年。疼痛通常定位明确,但严重程度差异很大。除疼痛外,大多数持续性腰痛患者还报告有各种运动和感觉功能障碍。患者在工作、娱乐和家庭中也报告有明显的功能损害。然而,典型患者并未表现出明显的心理困扰。大多数患者咨询过多个医疗服务提供者,接受过各种治疗,并使用过各种药物来缓解疼痛;少数患者接受过更积极的治疗措施,包括手术、椎间盘内治疗以及麻醉和精神活性药物。这些治疗均未取得成效。对这些患者进行体格检查并不能为做出明确诊断提供重要线索。肌肉痉挛、压痛和触发点等非特异性异常很常见,但下肢运动无力和感觉功能障碍以及膝关节和踝关节的反射改变则不太常见。即使三分之一的患者被诊断为椎间盘突出症,与特定突出椎间盘相关的反射改变、运动无力和感觉功能障碍的典型组合也极为罕见。诊断性影像学研究表明,大多数持续性腰痛患者存在涉及神经根受压或腰椎不稳或两者皆有的脊柱关节病异常,神经根受压是症状的主要原因。肌筋膜综合征和腰椎不稳是其次最常见的诊断。在经过脊柱疾病专家的全面评估后,五分之三的持续性腰痛患者被开具了额外疗程的保守治疗,五分之一的患者被开具了手术治疗,其余患者未接受任何治疗。持续性腰痛患者似乎是一类独特的腰痛患者群体,他们不同于具有类似非持续性急性症状的患者以及具有以明显行为和心理共病为特征的慢性疼痛综合征的患者。