el-Hajj G, Anneroth G
Department of Oral Pathology, Umeå University, Sweden.
Int J Oral Maxillofac Surg. 1996 Apr;25(2):124-9. doi: 10.1016/s0901-5027(96)80057-9.
Including 25 recurrences, the material comprised 87 odontogenic keratocysts (OKCs) from 57 patients, who had been treated in 1974-93. The study included an analysis of clinical and histologic data from the patients' records and from pathologic reports. The men:women ratio was 1.5:1. Most of the patients belonged to the age groups 10-19, 20-29, 40-49, and 60-69 years. Almost 75% of the OKCs were localized in the mandible. The most common site was the angle and ascending ramus area. Recurrences comprised 30.5% of the OKCs. The symphysial area of the mandible had the highest recurrence rate (50%). The diagnosis of Gorlin's syndrome was established in two patients. The recurrence rates for the OKCs that were removed in one or in several pieces were 27.5% and 39%, respectively. In 14/87 (16%) cases, microkeratocysts were histologically found. Parakeratosis was observed in 78/87 (89.5%), ortho- and parakeratosis in 6/87 (7%), and orthokeratosis in 3/87 (3.5%) cases. The recurrence rates were 31.5% and 41% for the OKCs that were removed during 1974, 1984, and 1985-90, respectively. In no case could malignant changes be observed at histologic examination.
该材料包括来自57例患者的87个牙源性角化囊肿（OKC），其中有25例复发，这些患者于1974年至1993年接受治疗。该研究包括对患者病历和病理报告中的临床和组织学数据进行分析。男女比例为1.5:1。大多数患者属于10 - 19岁、20 - 29岁、40 - 49岁和60 - 69岁年龄组。几乎75%的OKC位于下颌骨。最常见的部位是角部和升支区域。复发占OKC的30.5%。下颌骨的正中联合区域复发率最高（50%）。两名患者被诊断为戈林综合征。整块切除和分块切除的OKC复发率分别为27.5%和39%。在14/87（16%）的病例中，组织学上发现了微角化囊肿。78/87（89.5%）的病例观察到不全角化，6/87（7%）的病例观察到正角化和不全角化，3/87（3.5%）的病例观察到正角化。1974年、1984年以及1985 - 1990年期间切除的OKC复发率分别为31.5%和41%。组织学检查未发现恶变情况。
