Emmens R K, Richardson D, Thomas W, Hunter S, Hennigar R A, Wingard J R, Nolte F S
Department of Pathology and Laboratory Medicine, Emory University, School of Medicine, Atlanta, Georgia, USA.
J Clin Microbiol. 1996 May;34(5):1330-2. doi: 10.1128/jcm.34.5.1330-1332.1996.
We describe a necrotizing cerebritis in an allogeneic bone marrow transplant recipient caused by the neurotropic, dematiaceous fungus Cladophialophora bantiana. The patient presented 7 months after bone marrow transplantation with fever and sudden onset of left-sided weakness, followed shortly by cranial nerve III and VI palsies. The patient had a lesion (3.0 by 2.0 by 2.0 cm) of the right midbrain with extension to the pons, the left brain stem, and the right superior and the middle cerebellar peduncles. The diagnosis was made by microscopic examination and culture of a brain biopsy.
我们描述了一例同种异体骨髓移植受者发生的坏死性脑炎，由嗜神经性、暗色真菌班替枝孢霉（Cladophialophora bantiana）引起。该患者在骨髓移植7个月后出现发热，突发左侧肢体无力，随后不久出现动眼神经和展神经麻痹。患者右中脑有一病灶（3.0×2.0×2.0 cm），延伸至脑桥、左侧脑干以及右侧上、中小脑脚。通过脑活检的显微镜检查和培养做出了诊断。
