Rabinovitch M, Veras P S
Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York 10021-6399, USA.
Trends Microbiol. 1996 Apr;4(4):158-61. doi: 10.1016/0966-842x(96)10027-5.
Intracellular pathogens customize the composition and function of the vacuoles they occupy, and can arrest or distort vacuolar maturation. In doubly infected cells, vacuoles that contain two different parasites can be used to test for exclusionary mechanisms, for expression of vacuolar phenotypes that permit or restrict fusion, and for the survival of pathogens targeted to an unusual cellular compartment.
细胞内病原体可定制它们所占据的液泡的组成和功能，并能阻止或扭曲液泡成熟。在双重感染的细胞中，含有两种不同寄生虫的液泡可用于测试排斥机制、允许或限制融合的液泡表型的表达，以及定位于异常细胞区室的病原体的存活情况。
