内毒素促使造血干细胞（集落形成单位 - 细胞）进入人体外周血。
Mobilization of hematopoietic stem cells (CFU-C) into the peripheral blood of man by endotoxin.
作者信息
Cline M J, Golde D W
出版信息
Exp Hematol. 1977 May;5(3):186-90.
PMID:872907
Abstract
Pseudomonas endotoxin was administered to three normal subjects in order to assess possible effects on stem cell circulation. Increased numbers of granulopoietic stem cells (CFU-C) transiently appeared in the peripheral blood, reaching a maximum after the time of maximal leukopenia. There was a mean 4-fold increase in CFU-C per ml of blood following endotoxin. A high proportion of these CFU-C did not require an added source of colony-stimulating activity for growth in agar.
摘要
为了评估对干细胞循环可能产生的影响，将铜绿假单胞菌内毒素注射给三名正常受试者。外周血中粒细胞生成干细胞（CFU-C）数量短暂增加，在白细胞减少最严重时达到最大值。内毒素注射后，每毫升血液中的CFU-C平均增加了4倍。这些CFU-C中有很大一部分在琼脂中生长时不需要额外添加集落刺激活性物质。
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