Kusche J, Richter H, Thermann M, Reimann H J, Hesterberg R, Lorenz W
Chir Forum Exp Klin Forsch. 1977 Apr:157-60.
During intestinal ischemia in rabbits histamine concentration and diamine oxidase activity were altered in the intestinal wall and in the perfusate of mesenteric vessels. The results were interpreted as a histamine release and an increased catabolism of diamine oxidase. Thus, the combination of release of vasoactive histamine and partial elimination of a protective enzyme may contribute to the fatal outcome after mesenteric ischemia.
在兔肠缺血期间,肠壁和肠系膜血管灌流液中的组胺浓度和二胺氧化酶活性发生了改变。这些结果被解释为组胺释放以及二胺氧化酶分解代谢增加。因此,血管活性组胺的释放与一种保护酶的部分消除相结合,可能导致肠系膜缺血后的致命后果。