固有免疫中的集合
The collectins in innate immunity.
作者信息
Epstein J, Eichbaum Q, Sheriff S, Ezekowitz R A
机构信息
Department of Pediatrics, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
出版信息
Curr Opin Immunol. 1996 Feb;8(1):29-35. doi: 10.1016/s0952-7915(96)80101-4.
PMID:8729443
Abstract
The collectins are proteins with collagen tails and globular lectin domains that appear to play an important role in mammalian first line host defense. Recent insights have clarified the structural basis of ligand recognition, the interactions of collectins with complement cascades, and the association with disease susceptibility.
摘要
凝集素是一类具有胶原尾巴和球状凝集素结构域的蛋白质，它们似乎在哺乳动物的一线宿主防御中发挥着重要作用。最近的研究见解阐明了配体识别的结构基础、凝集素与补体级联反应的相互作用以及与疾病易感性的关联。
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