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A lectin from the mussel Mytilus galloprovincialis has a highly novel primary structure and induces glycan-mediated cytotoxicity of globotriaosylceramide-expressing lymphoma cells.来自贻贝（Mytilus galloprovincialis）的凝集素具有高度新颖的一级结构，并诱导表达神经节苷脂 GM3 的淋巴瘤细胞发生糖介导的细胞毒性。
J Biol Chem. 2012 Dec 28;287(53):44772-83. doi: 10.1074/jbc.M112.418012. Epub 2012 Oct 23.
2
Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivo.金合欢素在体外和体内抑制日本脑炎病毒感染。
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3
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4
Cytotoxicity and glycan-binding properties of an 18 kDa lectin isolated from the marine sponge Halichondria okadai.从海洋海绵 Halichondria okadai 中分离得到的 18 kDa 凝集素的细胞毒性和糖结合特性。
Toxins (Basel). 2012 May;4(5):323-38. doi: 10.3390/toxins4050323. Epub 2012 Apr 30.
5
Cytokine production induced by marine algae lectins in BALB/c mice splenocytes.海洋藻类凝集素诱导BALB/c小鼠脾细胞产生细胞因子
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Diversified carbohydrate-binding lectins from marine resources.来自海洋资源的多样化碳水化合物结合凝集素。
J Amino Acids. 2011;2011:838914. doi: 10.4061/2011/838914. Epub 2011 Nov 15.
8
Griffithsin has antiviral activity against hepatitis C virus.格氏乳香素有抗丙型肝炎病毒的活性。
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Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate.格里菲辛与人细胞相互作用的研究证实，它作为一种杀微生物剂候选物具有突出的安全性和疗效。
PLoS One. 2011;6(8):e22635. doi: 10.1371/journal.pone.0022635. Epub 2011 Aug 2.
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Diverse lectin repertoires in tunicates mediate broad recognition and effector innate immune responses.被囊动物中多样化的凝集素库介导广泛的识别和效应先天免疫反应。
Integr Comp Biol. 2003 Apr;43(2):323-30. doi: 10.1093/icb/43.2.323.

海洋水生生物的凝集素。

Lectins of marine hydrobionts.

机构信息

Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok 690022, Russia.

出版信息

Biochemistry (Mosc). 2013 Jul;78(7):760-70. doi: 10.1134/S0006297913070080.

DOI:10.1134/S0006297913070080
PMID:24010839
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7088153/
Abstract

Data from the literature and results of our research on lectins isolated from some kinds of marine hydrobionts such as clams, ascidians, sea worms, sponges, and algae are presented in this review. Results of comparative analysis of the basic physicochemical properties and biological activity of lectins isolated from various sources are discussed.

摘要

本综述介绍了从贝类、海鞘、海蚯蚓、海绵和藻类等海洋水生生物中分离得到的凝集素的文献数据和我们的研究结果。讨论了比较分析不同来源分离得到的凝集素的基本理化性质和生物活性的结果。