C57BL/6ByJ和129/J小鼠的乙醇摄入量与味觉偏好
Ethanol consumption and taste preferences in C57BL/6ByJ and 129/J mice.
作者信息
Bachmanov A A, Tordoff M G, Beauchamp G K
机构信息
Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104-3308, USA.
出版信息
Alcohol Clin Exp Res. 1996 Apr;20(2):201-6. doi: 10.1111/j.1530-0277.1996.tb01630.x.
Abstract
Mice of the C57BL/6ByJ (B6) and 129/J (129) strains were offered different concentrations of taste solutions in 48-hr, two-bottle choice tests. In comparison with the 129 strain, the B6 strain had higher preferences for ethanol, sucrose, and citric acid. They had lower preferences for NaCl and similar preferences for capsaicin and quinine hydrochloride. These data are consistent with the hypothesis that the higher ethanol intake by B6 mice depends, in part, on higher hedonic attractiveness of its sweet taste component.
摘要
在48小时的双瓶选择测试中，向C57BL/6ByJ（B6）和129/J（129）品系的小鼠提供不同浓度的味觉溶液。与129品系相比，B6品系对乙醇、蔗糖和柠檬酸的偏好更高。它们对氯化钠的偏好较低，对辣椒素和盐酸奎宁的偏好相似。这些数据与以下假设一致，即B6小鼠较高的乙醇摄入量部分取决于其甜味成分较高的享乐吸引力。
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