Zeng J, Zhang Y S, Pomer S, Staehler G, Ren D H
Department of Urological Surgery, Tongji Hospital, Wuhan.
J Tongji Med Univ. 1995;15(2):112-6. doi: 10.1007/BF02887914.
We performed thymectomy on the immature and mature male mice and made a quantitative assay of various germ cells of the seminiferous epithelium in the testis with Image Analyser System 35 days following thymectomy. The results indicated that as compared with the control group, all germ cells of the spermatogenesis lineage decreased in the immature group and in the mature group after thymectomy. The present study showed that thymus and its hormone stimulated not only the mitotic division, but also the meiotic division of germ cells during spermatogenesis, suggesting that thymus-sexual axis may play an important role in the process of spermatogenesis in the testis.
我们对未成熟和成熟雄性小鼠实施了胸腺切除术，并在胸腺切除术后35天，使用图像分析系统对睾丸生精上皮中的各种生殖细胞进行了定量分析。结果表明，与对照组相比，未成熟组和成熟组在胸腺切除术后，生精谱系中的所有生殖细胞均减少。本研究表明，胸腺及其激素不仅刺激生殖细胞在生精过程中的有丝分裂，还刺激其减数分裂，提示胸腺-性腺轴可能在睾丸生精过程中发挥重要作用。
