Zeng J, Zhang Y S, Zhuang Q Y, Zhou S W
Department of Urology, Tongji Hospital, Tongji Medical University, Wuhan.
J Tongji Med Univ. 1993;13(1):40-4. doi: 10.1007/BF02886592.
Hormonal abnormality in experimental varicocele induced by partial ligation of left renal vein and the effect of thymosin (fraction 5) on the secretion of the sexual hormone were studied in rats. Serum testosterone level was lowered after varicocele formation, but could be reversed or increased by intraperitoneal administration of thymosin 5 mg/rat twice a week for 4 weeks with concomitant increase of testicular testosterone content. Changes in FSH and LH both in serum and testis, determined with immunoassay method as that of testosterone, were insignificant as compared with control or thymosin treated groups.
研究了左肾静脉部分结扎诱导的实验性精索静脉曲张中的激素异常以及胸腺素（5组分）对性激素分泌的影响。在大鼠中进行实验，精索静脉曲张形成后血清睾酮水平降低，但通过每周两次腹腔注射5mg/大鼠胸腺素，持续4周，血清睾酮水平可得到逆转或升高，同时睾丸睾酮含量也增加。与对照组或胸腺素治疗组相比，采用与睾酮相同的免疫测定方法测定的血清和睾丸中促卵泡激素（FSH）和促黄体生成素（LH）的变化不显著。
