Vettorazzi G, Almeida W F, Burin G J, Jaeger R B, Puga F R, Rahde A F, Reyes F G, Schvartsman S
International Toxicology Information Centre, San Sebastian, Spain.
Teratog Carcinog Mutagen. 1995;15(6):313-37. doi: 10.1002/(SICI)1520-6866(1996)15:6<313::AID-TCM7>3.0.CO;2-L.
For the last 30 years the Joint FAO/WHO Meeting on Pesticide Residues (JMPR) has carried out toxicological evaluations and safety assessments of dithiocarbamate pesticides, continuously adjusting previous appraisals in the light of new data and advances in the understanding of the principles and mechanisms of toxic action of these compounds. The historical narrative of the evaluative process is followed by an account of the present international safety assessment status of the dithiocarbamate pesticides so far examined by the JMPR. They are ferbam, mancozeb, maneb, metiram, nabam, propineb, thiram, zineb, ziram, and the associated substances, ethylenethiourea (ETU) and propylenethiourea (PTU).
在过去30年里，粮农组织/世界卫生组织农药残留联席会议（JMPR）对二硫代氨基甲酸盐类农药进行了毒理学评估和安全性评价，并根据新数据以及对这些化合物毒性作用原理和机制认识的进展，不断调整先前的评估。在介绍评估过程的历史沿革之后，本文阐述了JMPR迄今已审查的二硫代氨基甲酸盐类农药目前的国际安全性评价状况。这些农药包括福美铁、代森锰锌、代森锰、代森联、福美钠、丙森锌、福美双、代森锌、福美锌，以及相关物质乙撑硫脲（ETU）和丙撑硫脲（PTU）。
