A unifying hypothesis for the mechanism of NSAID related gastrointestinal toxicity.
作者信息
Mahmud T, Scott D L, Bjarnason I
机构信息
Department of Rheumatology, King's College School of Medicine and Dentistry, London, United Kingdom.
出版信息
Ann Rheum Dis. 1996 Apr;55(4):211-3. doi: 10.1136/ard.55.4.211.
Abstract
摘要
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本文引用的文献
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BIOCHEMICAL PROPERTIES OF ANTI-INFLAMMATORY DRUGS--III. UNCOUPLING OF OXIDATIVE PHOSPHORYLATION IN A CONNECTIVE TISSUE (CARTILAGE) AND LIVER MITOCHONDRIA BY SALICYLATE ANALOGUES: RELATIONSHIP OF STRUCTURE TO ACTIVITY.抗炎药物的生化特性——III. 水杨酸类似物对结缔组织（软骨）和肝脏线粒体氧化磷酸化的解偶联作用：结构与活性的关系
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Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans.非甾体抗炎药对人体小肠和大肠的副作用。
Gastroenterology. 1993 Jun;104(6):1832-47. doi: 10.1016/0016-5085(93)90667-2.
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Omeprazole ameliorates aspirin-induced gastroduodenal injury.奥美拉唑可改善阿司匹林所致的胃十二指肠损伤。
Dig Dis Sci. 1994 Jan;39(1):97-103. doi: 10.1007/BF02090067.
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Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat.在大鼠中具有显著降低致溃疡特性的新型非甾体抗炎药衍生物。
Gastroenterology. 1994 Jul;107(1):173-9. doi: 10.1016/0016-5085(94)90074-4.
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Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase.人环氧化酶组成型和诱导型的表达及选择性抑制
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A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.一种释放一氧化氮的非甾体抗炎药可加速大鼠胃溃疡的愈合。
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Occluding junctions and cytoskeletal components in a cultured transporting epithelium.培养的转运上皮中的紧密连接和细胞骨架成分。
J Cell Biol. 1980 Dec;87(3 Pt 1):746-54. doi: 10.1083/jcb.87.3.746.
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Role of bacteria in gastric ulceration produced by indomethacin in the rat: cytoprotective action of antibiotics.细菌在吲哚美辛所致大鼠胃溃疡形成中的作用：抗生素的细胞保护作用
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Aspirin can inhibit gastric mucosal cyclo-oxygenase without causing lesions in rat.阿司匹林可抑制大鼠胃黏膜环氧化酶而不引起损伤。
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