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过去一百年间挪威饮食与冠心病的关系。

The Norwegian diet during the last hundred years in relation to coronary heart disease.

作者信息

Johansson L, Drevon C A, Aa Bjørneboe G E

机构信息

National Nutrition Council, Oslo, Norway.

出版信息

Eur J Clin Nutr. 1996 May;50(5):277-83.

PMID:8735307
Abstract

OBJECTIVE

The influence of dietary changes on serum cholesterol and CHD during the last century in Norway has been evaluated.

DESIGN

Data on food consumption are based on national food supply and household consumption surveys. To be able to calculate comparable series of the dietary content of energy, fat, saturated, monounsaturated and polyunsaturated fatty acids and dietary cholesterol, we compiled food composition data covering this century. The dietary effect on serum cholesterol was estimated by Keys equation.

RESULTS

Changes in dietary lipids precede the increase and the decrease in mortality of CHD. The estimated serum cholesterol level in the population increased by approximately 1 mmol/l during 1900-1960, and decreased by approximately 0.6 mmol/l during 1960-1992. These changes correspond to a 60% increase and a 30% decrease in risk for CHD. However, the observed change in mortality of CHD was greater. During 1951-1955 and 1971-1975 it increased by 120% in men and 80% in women aged 50-59 years and during 1971-1975 and 1991-1993 it decreased by 43% and 29%, respectively.

CONCLUSIONS

Change in dietary lipids have the potential to explain a great deal of the changes in mortality of CHD in Norway during this century. A reduced consumption of boiled coffee and an increase in the consumption of antioxidants may also have contributed to the reduced mortality of CHD the last 20 years.

摘要

目的

评估上个世纪挪威饮食变化对血清胆固醇和冠心病的影响。

设计

食物消费数据基于国家食物供应和家庭消费调查。为了能够计算能量、脂肪、饱和脂肪酸、单不饱和脂肪酸、多不饱和脂肪酸以及膳食胆固醇的可比膳食含量系列,我们汇编了涵盖本世纪的食物成分数据。通过凯斯方程估算饮食对血清胆固醇的影响。

结果

膳食脂质的变化先于冠心病死亡率的上升和下降。在1900年至1960年期间,人群中估计的血清胆固醇水平大约升高了1毫摩尔/升,在1960年至1992年期间大约降低了0.6毫摩尔/升。这些变化分别对应冠心病风险增加60%和降低30%。然而,观察到的冠心病死亡率变化更大。在1951年至1955年以及1971年至1975年期间,50至59岁男性的冠心病死亡率上升了120%,女性上升了80%;在1971年至1975年以及1991年至1993年期间,分别下降了43%和29%。

结论

膳食脂质的变化有可能解释本世纪挪威冠心病死亡率的大量变化。煮咖啡消费量的减少以及抗氧化剂消费量的增加也可能对过去20年冠心病死亡率的降低起到了作用。

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