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科威特蒙面女性的维生素D缺乏症

Vitamin D deficiency in veiled Kuwaiti women.

作者信息

el-Sonbaty M R, Abdul-Ghaffar N U

机构信息

Medical Department, Adan Hospital, Kuwait.

出版信息

Eur J Clin Nutr. 1996 May;50(5):315-8.

PMID:8735313
Abstract

OBJECTIVE

To study vitamin D deficiency in veiled Kuwaiti women.

DESIGN

Prospective on cases and volunteers.

SETTING

The medical department in a general hospital in Kuwait serving about 300000 persons (Adan Hospital).

SUBJECTS

The authors saw four cases of unexplained vitamin D deficiency osteomalacia in otherwise healthy veiled Kuwaiti women. This stimulated us to study 50 veiled volunteer Kuwaiti women aged between 14 and 45 years old who had three children or less, and 22 unveiled volunteer Kuwaiti women with matched age and number of children as control.

INTERVENTIONS

Blood samples were taken to check levels of 25-hydroxy cholecalciferol, calcium, phosphorus and alkaline phosphatase. Blood urea, serum creatinine, serum bilirubin, serum alanine transaminase, serum aspartate transaminase, serum lactic dehydroginase, prothrombin time, urine for proteins and pH were checked to exclude renal and hepatic disease.

RESULTS

showed subclinical vitamin D deficiency among veiled women and two cases of clinically overt osteomalacia were discovered among the veiled volunteers suggesting a high prevalence of the disease among veiled Kuwaiti women.

摘要

目的

研究科威特戴面纱女性的维生素D缺乏情况。

设计

病例与志愿者前瞻性研究。

地点

科威特一家为约30万人服务的综合医院的内科(阿丹医院)。

研究对象

作者发现4例原本健康的科威特戴面纱女性患有不明原因的维生素D缺乏性骨软化症。这促使我们对50名年龄在14至45岁之间、育有三个及以下子女的科威特戴面纱志愿者女性,以及22名年龄和子女数量匹配的未戴面纱科威特志愿者女性作为对照进行研究。

干预措施

采集血样以检测25-羟胆钙化醇、钙、磷和碱性磷酸酶水平。检查血尿素、血清肌酐、血清胆红素、血清丙氨酸转氨酶、血清天冬氨酸转氨酶、血清乳酸脱氢酶、凝血酶原时间、尿蛋白和pH值以排除肾脏和肝脏疾病。

结果

显示戴面纱女性存在亚临床维生素D缺乏,并且在戴面纱的志愿者中发现了2例临床显性骨软化症病例,提示该疾病在科威特戴面纱女性中患病率较高。

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