Ramani R, Ramani A, Shivananda P G
Dept of Microbiology, Kasturba Medical College, Manipal, Karnataka.
J Postgrad Med. 1994 Apr-Jun;40(2):87-8.
Onychomycosis caused by mould infection is rare. A 40 year old male patient presented with dystrophic finger nails and multiple, erythematous lesions with slightly raised borders and scaling all over the body. The patient was a known diabetic. He did not respond to griseofulvin. Samples from nails and skin scales were cultured. From the nails, Penicillium species and from the skin scales. Trichophyton rubrum were isolated. Ketoconazole therapy (200 mg twice daily x 4 mths) led to complete cure with negative cultures and normalization of nails.
由霉菌感染引起的甲癣较为罕见。一名40岁男性患者出现指甲营养不良，全身有多处边界略隆起且有鳞屑的红斑性病变。该患者为已知糖尿病患者。他对灰黄霉素治疗无反应。对指甲和皮肤鳞屑样本进行培养。从指甲中分离出青霉属菌种，从皮肤鳞屑中分离出红色毛癣菌。酮康唑治疗（每日2次，每次200毫克，共4个月）使培养结果转阴，指甲恢复正常，实现了完全治愈。
