Knüttgen D, Burgwinkel W, Nieden K Z, Jahn M, Müller-Gorges M R, Doehn M
Department of Anesthesiology, Kliniken der Stadt Köln, Krankenhaus Merheim, Germany.
Int J Clin Monit Comput. 1996 Feb;13(1):21-5. doi: 10.1007/BF02918208.
The aim of the study was to investigate whether peripheral nerve dysfunction can influence the applicability of the DATEX Relaxograph in diabetics. Sixty two patients (43 diabetics, 19 non-diabetics) undergoing ophthalmosurgical procedures under general anesthesia were tested. The distal motor latency (DML) of the ulnar nerve served as a graduation tool for peripheral nerve dysfunction. The patients were divided in three groups: non-diabetics (group 1), diabetics with DML < 3.8 msec (group 2), diabetics with DML > 3.8 msec (group 3). Relaxometry was performed by stimulating the right ulnar nerve near the wrist, and the evoked response (EMG) was obtained from the hypothenar muscle. Calibration of the device (i.e. supramaximal stimulation within the given current range of a maximum of 70 mA) was carried out successfully in most patients of group 1 and 2 (94.7% and 85.7% respectively). In contrast to that calibration could be carried out in only 40.9% of the patients of group 3 (P < 0.01 vs. group 1 and 2). Consequently in a high percentage (59.1%) of the patients of group 3 relaxometry had to be performed in an uncalibrated manner. The results substantiate the hypothesis that peripheral nerve dysfunction can restrict the applicability of the Relaxograph in diabetics.
该研究的目的是调查周围神经功能障碍是否会影响DATEX Relaxograph在糖尿病患者中的适用性。对62例接受全身麻醉下眼科手术的患者（43例糖尿病患者，19例非糖尿病患者）进行了测试。尺神经的远端运动潜伏期（DML）作为周围神经功能障碍的分级工具。患者分为三组：非糖尿病患者（第1组）、DML<3.8毫秒的糖尿病患者（第2组）、DML>3.8毫秒的糖尿病患者（第3组）。通过刺激腕部附近的右侧尺神经进行松弛测量，并从小鱼际肌获得诱发反应（肌电图）。在第1组和第2组的大多数患者中（分别为94.7%和85.7%）成功进行了设备校准（即在给定电流范围内最大70毫安的超强刺激）。相比之下，第3组只有40.9%的患者能够进行校准（与第1组和第2组相比，P<0.01）。因此，在第3组的高比例（59.1%）患者中，松弛测量不得不以未校准的方式进行。结果证实了周围神经功能障碍会限制Relaxograph在糖尿病患者中适用性的假设。
